Journal
JACC-CARDIOVASCULAR INTERVENTIONS
Volume 2, Issue 11, Pages 1035-1046Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jcin.2009.06.019
Keywords
optical coherence tomography; coronary; stent; atherosclerosis
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Funding
- NHLBI NIH HHS [R01 HL114406, R21 HL108263, R37 HL057506] Funding Source: Medline
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Cardiovascular optical coherence tomography (OCT) is a catheter-based invasive imaging system. Using light rather than ultrasound, OCT produces high-resolution in vivo images of coronary arteries and deployed stents. This comprehensive review will assist practicing interventional cardiologists in understanding the technical aspects of OCT based upon the physics of light and will also highlight the emerging research and clinical applications of OCT. Semi-automated imaging analyses of OCT systems permit accurate measurements of luminal architecture and provide insights regarding stent apposition, overlap, neointimal thickening, and, in the case of bioabsorbable stents, information regarding the time course of stent dissolution. The advantages and limitations of this new imaging modality will be discussed with emphasis on key physical and technical aspects of intracoronary image acquisition, current applications, definitions, pitfalls, and future directions. (J Am Coll Cardiol Intv 2009;2:1035-46)
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