Journal
IRISH JOURNAL OF MEDICAL SCIENCE
Volume 182, Issue 1, Pages 1-6Publisher
SPRINGER LONDON LTD
DOI: 10.1007/s11845-012-0865-y
Keywords
Functional gastrointestinal disorders; Irritable bowel syndrome; Microbiota; Cytokines; Gut-brain axis
Categories
Funding
- Science Foundation Ireland
Ask authors/readers for more resources
Gastrointestinal symptoms such as heartburn, indigestion (or dyspepsia), bloating, distension, constipation, abdominal pain, abdominal discomfort and diarrhoea are extremely common worldwide. For some, such symptoms can prove to be chronic and disabling. The recent literature on irritable bowel syndrome and, in particular, work emanating form this authors research group, was reviewed. These functional symptoms commonly occur in aggregations, referred to as functional gastrointestinal disorders (FGIDs). Some of the FGIDs and, most notably irritable bowel syndrome (IBS), have achieved a degree of scientific and clinical credibility as coherent entities. Several lines of evidence ranging from gut motility to the microbiota are under investigation in attempts to explain IBS or its symptomatology. Though biomarkers for IBS and other FGIDs have proven elusive, considerable progress has been made in understanding possible aetiological factors in IBS; progress which may well lead to better therapeutic strategies.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available