Characterizing changes in kidney and renal pelvis cancer incidence from 1998 to 2006 in the United States

In this study, we characterize the changes in kidney and renal pelvis cancer (RCC) from 1998 to 2006 in the United States. The goal is to examine variations in stage and treatments. In addition, we explore changes in risk factors that have occurred over the same period. Data on over 20,000 patients diagnosed with RCC in National Cancer Data Base were used for the study. We investigated the changes in stage and treatment rates based on race, gender and age at diagnosis from 1998 to 2006. Changes in smoking, obesity and hypertension rates over the period were examined for comparison. The increase in RCC incidence rates from 1998 to 2006 was almost entirely a result of increases in stage I. Increases for blacks were proportionally higher than whites. Obesity and hypertension increased over the period but smoking declined. In terms of treatment, there was an increase in surgery cases primarily for stage I. There were no significant differences in trends based on gender, although rates in men were 65% greater than in women. The mean age at diagnosis was stable for stages I-IV. There are increased incidences of renal tumors, particularly stage I renal cancer among blacks and whites from 1998 to 2006. Patients were more likely to undergo surgical therapy for these tumors.