4.6 Review

Blood biomarkers in stroke: research and clinical practice

Journal

INTERNATIONAL JOURNAL OF STROKE
Volume 7, Issue 5, Pages 435-439

Publisher

SAGE PUBLICATIONS LTD
DOI: 10.1111/j.1747-4949.2012.00784.x

Keywords

biomarker; diagnosis; prediction; research; stroke

Funding

  1. Chief Scientist's Office (CSO) [CAF/06/30]
  2. MRC Clinician Scientist Fellowship [G0902303]
  3. Chief Scientist Office [CAF/06/30] Funding Source: researchfish
  4. Medical Research Council [G0902303] Funding Source: researchfish
  5. MRC [G0902303] Funding Source: UKRI

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Blood biomarkers may have applications in stroke diagnosis, outcome prediction, or treatment. In this article, we provide a focused review on some of the methodological challenges and potential developments of biomarkers in stroke. We review the approaches to the development of a diagnostic blood marker: a candidate marker approach, marker panels, and omics. Then we examined the role of blood markers to predict recurrent stroke and treatment response in stroke.

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