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Potent and Orally Active Small-Molecule Inhibitors of the MDM2-p53 Interaction
Shanghai Yu et al.
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Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity
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Stereoselective Synthesis of Spirocyclic Oxindoles via Prins Cyclizations
M. Paola Castaldi et al.
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Stereocontrolled Synthesis of Spirooxindoles through Lewis Acid-Promoted [5+2]-Annulation of Chiral Silyl Alcohols
Yun Zhang et al.
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Spirooxindoles: reaction of 2,6-diaminopyrimidin-4(3H)-one and isatins
Khosrow Jadidi et al.
TETRAHEDRON (2009)
Synthesis of spiro[benzopyrazolonaphthyridine-indoline]-diones and spiro[chromenopyrazolopyridine-indoline]-diones by one-pot, three-component methods in water
Somayeh Ahadi et al.
TETRAHEDRON (2009)
Pd-catalyzed intramolecular amidation of 2-(buta-1,3-dienyl)phenylcarbamoyl chloride: a concise synthesis of spiro[indoline-3,3′-pyrrolidine]
Haruhi Kamisaki et al.
TETRAHEDRON LETTERS (2009)
Isolation, structure elucidation, and biomimetic total synthesis of versicolamide B, and the isolation of antipodal (-)-stephacidin A and (+)-notoamide B from Aspergillus versicolor NRRL 35600
Thomas J. Greshock et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2008)
Versatile three-component procedure for combinatorial synthesis of 2-aminospiro[(3′H)-indol-3′,4-(4H)-pyrans]
Yuri M. Litvinov et al.
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Synthesis of maremycins A and D1 via cycloaddition of a nitrone with (E)-3-ethylidene-1-methylindolin-2-one
Tohru Ueda et al.
ORGANIC LETTERS (2008)
Synthesis of fused 2'-amino-3'-R-spiro-[indole-3,4'-pyran]-2(1H)-ones
L. A. Shemchuk et al.
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY (2008)
An easy access to novel steroidal dispiropyrrolidines through 1,3-dipolar cycloaddition of azomethine ylides
A. R. Suresh Babu et al.
TETRAHEDRON LETTERS (2008)
Stereoselective synthesis of (R)-(+)-1-methoxyspirobrassinin, (2R,3R)-(-)-1-methoxyspirobrassinol methyl ether and their enantiomers or diastereoisomers
Zuzana C. Curillova et al.
TETRAHEDRON LETTERS (2007)
Synthesis and molecular structure of spirocyclic 2-oxindole derivatives of 2-amino-4H-pyran condensed with the pyrazolic nucleus
Ruslan Gr. Redkin et al.
TETRAHEDRON (2007)
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Martin Pettersson et al.
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Enantioselective construction of spirocyclic oxindolic Cyclopentanes by palladium-catalyzed trimethylenemethane-[3+2]-cycloaddition
Barry M. Trost et al.
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Synthesis of novel functionalized 3-spiropyrrolizidine and 3-spiropyrrolidine oxindoles from baylis-hillman adducts of isatin and heteroaldehydes with azomethine ylides via [3+2]-cycloaddition
Ponnusamy Shanmugam et al.
ORGANIC LETTERS (2007)
Ultrasonic assisted-silica mediated [3+2] cycloaddition of azomethine ylides - a facile multicomponent one-pot synthesis of novel dispiroheterocycles
A. R. Suresh Babu et al.
TETRAHEDRON LETTERS (2007)
A simple and clean procedure for three-component synthesis of spirooxindoles in aqueous medium
Song-Lei Zhu et al.
TETRAHEDRON (2007)
Simple and one-pot protocol for synthesis of indene-spiro-oxindoles involving tandem Prins and Friedel-Crafts reactions
Deevi Basavaiah et al.
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Three-component synthesis and anticancer evaluation of polycyclic indenopyridines lead to the discovery of a novel indenoheterocycle with potent apoptosis inducing properties
Madhuri Manpadi et al.
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Chemical studies on monoterpenoid indole alkaloids from medicinal plant resources Gelsemium and Ophiorrhiza
Mariko Kitajima
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Synthesis of dispirooxindolecycloalka[d]pyrimidino[2,3-b]-thiazole pyrrolidine/thiapyrrolizidine ring systems
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Heteroyohimbinoid type oxindole alkaloids from Mitragyna parvifolia
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Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction
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Design, synthesis and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part I
T Jiang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Design, synthesis, and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part 2
T Jiang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Efficient entry to diversely functionalized spirocyclic oxindoles from isatins through carbonyl-addition/cyclization reaction sequences
B Alcaide et al.
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Absolute stereochemistry of citrinadins A and B from marine-derived fungus
T Mugishima et al.
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1,3-Dipolar cycloaddition reaction of heteroaromatic N-ylides with 3-[(E)-2-aryl(hetaryl)-2-oxoethylidene]indolin-2-ones
AB Serov et al.
RUSSIAN CHEMICAL BULLETIN (2005)
Chiral cruciferous phytoalexins:: Preparation, absolute configuration, and biological activity
K Monde et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2005)
Synthesis of spirooxindoles via asymmetric 1,3-dipolar cycloaddition
K Ding et al.
TETRAHEDRON LETTERS (2005)
Structure-based design of potent non-peptide MDM2 inhibitors
K Ding et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
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ME Heitzman et al.
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Preparation and synthetic applications of 2-halotryptamines: Synthesis of elacomine and isoelacomine
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ORGANIC LETTERS (2004)
Recognition of privileged structures by G-protein coupled receptors
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JOURNAL OF MEDICINAL CHEMISTRY (2004)
The three-component reaction between isatin, α-amino acids, and dipolarophiles
S Rehn et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2004)
A facile synthesis of novel dispiroheterocycles through solvent-free microwave-assisted [3+2] cycloaddition of azomethine ylides
J Jayashankaran et al.
TETRAHEDRON LETTERS (2004)
A library of spirooxindoles based on a stereoselective three-component coupling reaction
MMC Lo et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Concise, asymmetric total synthesis of spirotryprostatin A
T Onishi et al.
TETRAHEDRON (2004)
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CHEMICAL REVIEWS (2003)
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EM Beccalli et al.
TETRAHEDRON (2003)
Construction of spiro[pyrrolidine-3,3′-oxindoles] -: Recent applications to the synthesis of oxindole alkaloids
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EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2003)
Paraherquamides, brevianamides, and asperparalines: Laboratory synthesis and biosynthesis. An interim report
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ACCOUNTS OF CHEMICAL RESEARCH (2003)
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HETEROATOM CHEMISTRY (2003)
Spirocyclization strategy toward indole phytoalexins. The first synthesis of (±)-1-methoxyspirobrassinin, (±)-1-methoxyspirobrassinol, and (±)-1-methoxyspirobrassinol methyl ether
P Kutschy et al.
TETRAHEDRON LETTERS (2002)
Asymmetric, stereocontrolled total synthesis of (+) and (-)-spirotryprostatin B via a diastereoselective azomethine ylide [1,3]-dipolar cycloaddition reaction
PR Sebahar et al.
TETRAHEDRON (2002)
Pteropodine and isopteropodine positively modulate the function of rat muscarinic M1 and 5-HT2 receptors expressed in Xenopus oocyte
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EUROPEAN JOURNAL OF PHARMACOLOGY (2002)
Three-component 1,3-dipolar cycloaddition reactions in synthesis of spiro[pyrrolidine-2,3 '-oxindoline] derivatives
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HETEROATOM CHEMISTRY (2002)
Azomethine ylide cycloaddition/reductive heterocyclization approach to oxindole alkaloids: Asymmetric synthesis of (-)-horsfiline
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Total synthesis of SR 121463 A, a highly potent and selective vasopressin V2:: Receptor antagonist
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Synthesis, absolute configuration, and enantiomeric enrichment of a cruciferous oxindole phytoalexin, (S)-(-)-spirobrassinin, and its oxazoline analog
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JOURNAL OF ORGANIC CHEMISTRY (2001)
The chemistry of isatins: a review from 1975 to 1999
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JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY (2001)
2-Oxoindolin-3-ylidene derivatives as 2π components in 1,3-dipolar cycloadditions of azomethine ylides
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TETRAHEDRON (2001)
One-pot highly diastereoselective synthesis of new 2-substituted 8-(spiro-3 '-indolino-2 '-one)-pyrrolo[3,4-a]pyrrolizine-1,3-diones mediated by azomethine ylide induced by microwave irradiation
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SYNTHETIC COMMUNICATIONS (2001)
Lovastatin nonaketide synthase catalyzes an intramolecular Diels-Alder reaction of a substrate analogue
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JOURNAL OF ORGANIC CHEMISTRY (2000)
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PHYTOCHEMISTRY (2000)
An approach to some spiro oxindole alkaloids through cycloaddition reactions of 3-methylideneindolin-2-one
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AUSTRALIAN JOURNAL OF CHEMISTRY (2000)
Preparation and a novel rearrangement reaction of 1,2,3, 4-tetrahydro-9-hydroxy-beta-carboline, and their applications for the total synthesis of (+/-)-coerulescine
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