Journal
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Volume 76, Issue 3, Pages S10-S19Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.ijrobp.2009.07.1754
Keywords
QUANTEC; NTCP
Funding
- National Institutes of Health [CA85181, CA69579]
- Lance Armstrong Foundation
- NATIONAL CANCER INSTITUTE [R01CA129182, R29CA069579, R01CA069579, R29CA085181, R01CA085181] Funding Source: NIH RePORTER
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The Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC) review summarizes the currently available three-dimensional dose/volume/outcome data to update and refine the normal tissue dose/volume tolerance guidelines provided by the classic Emami et al. paper published in 1991. A clinician's view on using the QUANTEC information in a responsible manner is presented along with a description of the most commonly used normal tissue complication probability (NTCP) models. A summary of organ-specific dose/volume/outcome data, based on the QUANTEC reviews, is included. (C) 2010 Elsevier Inc.
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