Journal
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
Volume 62, Issue 11, Pages 565-571Publisher
TAYLOR & FRANCIS AS
DOI: 10.1080/00914037.2013.769160
Keywords
Anti cancer drug; drug delivery; hydrogels
Categories
Funding
- University Grants Commission (UGC), New Delhi under UGC-RFSMS [F 4-1/2006 (BSR)/11-23/2008 (BSR)]
Ask authors/readers for more resources
Hydrogels were prepared from 2-hydroxy ethyl methacrylate and acrylamidoglycolic acid using N,N'-methylene bis acrylamide as a crosslinking agent in presence of potassium persulfate initiator. The average molecular mass between crosslinks (M c) and polymer-solvent interaction parameter of hydrogels were determined from equilibrium swelling values. Fourier transform infrared spectroscopy of hydrogels shows the confirmation of the formation of co-polymeric hydrogels. Scanning electron microscopy of hydrogels shows the porous network structure. Differential scanning calorimetry and X-ray diffraction were performed to understand the crystalline nature of hydrogel and drug after encapsulation in to hydrogels. In vitro release studies indicated the release of 5-Fluorouracil for more than 12h.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available