Journal
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS
Volume 59, Issue 3, Pages 184-191Publisher
TAYLOR & FRANCIS AS
DOI: 10.1080/00914030903231332
Keywords
berberine; chitosan; complex membrane; sodium alginate
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Chitosan, sodium alginate and berberine complex membranes were prepared. The structure and properties of the drug-loaded membrane were studied using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and thermal gravimetric and differential thermal analysis (DTA). The drug-release property of membranes with different ratios of chitosan and sodium alginate was also investigated. The results show that when chitosan and sodium alginate were mixed in weight ratio of 5:1, a polyelectrolyte complex film was formed and exhibited better thermal stability and stronger control ability over drug release.
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