Journal
INTERNATIONAL JOURNAL OF PHARMACEUTICS
Volume 448, Issue 1, Pages 28-43Publisher
ELSEVIER
DOI: 10.1016/j.ijpharm.2013.03.006
Keywords
Liposomes; Cancer therapeutics; Drug delivery; Second generation
Categories
Funding
- Department of Biotechnology (DBT)
- Department of Science and Technology (DST)
- Ministry of Science and Technology, Government of India
- University Grants Commission, India
Ask authors/readers for more resources
Recent innovations and developments in nanotechnology have revolutionized cancer therapeutics. Engineered nanomaterials are the current workhorses in the emerging field of cancer nano-therapeutics. Lipid vesicles bearing anti-tumor drugs have turned out to be a clinically feasible and promising nano-therapeutic approach to treat cancer. Efficient entrapment of therapeutics, biocompatibility, biodegradability, low systemic toxicity, low immunogenicity and ability to bypass multidrug resistance mechanisms has made liposomes a versatile drug/gene delivery system in cancer chemotherapy. The present review attempts to explore the recent key advances in liposomal research and the vast arsenal of liposomal formulations currently being utilized in treatment and diagnosis of cancer. (C) 2013 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available