Journal
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
Volume 78, Issue 7, Pages 1115-1118Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.ijporl.2014.04.026
Keywords
Allergic rhinitis; Nasal saline irrigation; Seawater; Intranasal corticosteroids
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Funding
- Project of the Shanghai Committee of Science and Technology, China [12411952407]
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Objective: To evaluate the effect of nasal saline irrigation in the treatment of allergic rhinitis (AR) in children and to assess whether nasal saline irrigation could be used as a complementary therapy for AR in children in combination with the intranasal corticosteroids (INS). Method: In total, 61 children with AR were divided into three groups: the nasal irrigation, intranasal corticosteroid, and combined treatment groups. Symptoms and signs of AR and eosinophils (EOS) in the nasal secretions were evaluated after 4 weeks, 8 weeks, and 12 weeks of treatment. Results: In AR children treated with nasal irrigation and a decreased the INS dose, a significant improvement in symptoms and signs and a significant decrease in the mean EOS count in nasal secretions were observed at week 12. Conclusion: Nasal saline irrigation with physiological seawater is well tolerated and benefits the patients with AR, and can thus be considered a good adjunctive treatment option to maintain the effectiveness of the INS at a lower dose, thus resulting in reduced side effects and a decreased economic burden. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
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