4.7 Article

xiNET: Cross-link Network Maps With Residue Resolution

Journal

MOLECULAR & CELLULAR PROTEOMICS
Volume 14, Issue 4, Pages 1137-1147

Publisher

AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
DOI: 10.1074/mcp.O114.042259

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Funding

  1. Wellcome Trust [084229, 103139, 092076, 091020]

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xiNET is a visualization tool for exploring cross-linking/mass spectrometry results. The interactive maps of the cross-link network that it generates are a type of node-link diagram. In these maps xiNET displays: (1) residue resolution positional information including linkage sites and linked peptides; (2) all types of cross-linking reaction product; (3) ambiguous results; and, (4) additional sequence information such as domains. xiNET runs in a browser and exports vector graphics which can be edited in common drawing packages to create publication quality figures. Availability: xiNET is open source, released under the Apache version 2 license. Results can be viewed by uploading data to http://crosslinkviewer.org/or by downloading the software from http://github.com/colin-combe/crosslink-viewer and running it locally.

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