4.5 Review

Liver X receptors and fat cell metabolism

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Modulation of RXR function through ligand design

Efren Perez et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2012)

Article Endocrinology & Metabolism

Liver X receptors regulate de novo lipogenesis in a tissue-specific manner in C57BL/6 female mice

Marion Korach-Andre et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)

Article Endocrinology & Metabolism

Pathways regulated by glucocorticoids in omental and subcutaneous human adipose tissues: a microarray study

Mi-Jeong Lee et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)

Review Pharmacology & Pharmacy

Targeting liver X receptors in human health: deadlock or promising trail?

Emilie Viennois et al.

EXPERT OPINION ON THERAPEUTIC TARGETS (2011)

Article Biochemistry & Molecular Biology

CIDEA interacts with liver X receptors in white fat cells

Agne Kulyte et al.

FEBS LETTERS (2011)

Article Biochemistry & Molecular Biology

Liver X Receptor (LXR) Regulates Human Adipocyte Lipolysis

Britta M. Stenson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Multidisciplinary Sciences

Both liver-X receptor (LXR) isoforms control energy expenditure by regulating Brown Adipose Tissue activity

Marion Korach-Andre et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Immunology

Adipokines in inflammation and metabolic disease

Noriyuki Ouchi et al.

NATURE REVIEWS IMMUNOLOGY (2011)

Article Endocrinology & Metabolism

Separate and overlapping metabolic functions of LXRα and LXRβ in C57Bl/6 female mice

Marion Korach-Andre et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)

Article Endocrinology & Metabolism

Overexpression of nuclear receptor SHP in adipose tissues affects diet-induced obesity and adaptive thermogenesis

Imene Tabbi-Anneni et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)

Article Biochemistry & Molecular Biology

ADD1/SREBP1c activates the PGC1-α promoter in brown adipocytes

Qin Hao et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2010)

Review Chemistry, Medicinal

Liver X receptor modulators: a review of recently patented compounds (2007-2009)

Xiaolin Li et al.

EXPERT OPINION ON THERAPEUTIC PATENTS (2010)

Article Biochemistry & Molecular Biology

Group X secretory phospholipase A2 negatively regulates adipogenesis in murine models

Xia Li et al.

FASEB JOURNAL (2010)

Article Endocrinology & Metabolism

Cholesterol imbalance in adipocytes: a possible mechanism of adipocytes dysfunction in obesity

B. -L. Yu et al.

OBESITY REVIEWS (2010)

Review Biochemistry & Molecular Biology

The liver X receptor: Control of cellular lipid homeostasis and beyond Implications for drug design

Maaike H. Oosterveer et al.

PROGRESS IN LIPID RESEARCH (2010)

Article Endocrinology & Metabolism

Role of Receptor-Interacting Protein 140 in human fat cells

Niklas Mejhert et al.

BMC ENDOCRINE DISORDERS (2010)

Article Genetics & Heredity

Functional and genetic analysis in type 2 diabetes of Liver X receptor alleles - a cohort study

Ingrid Dahlman et al.

BMC MEDICAL GENETICS (2009)

Article Endocrinology & Metabolism

Activation of Liver X Receptor Regulates Substrate Oxidation in White Adipocytes

Britta M. Stenson et al.

ENDOCRINOLOGY (2009)

Article Biochemistry & Molecular Biology

Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia

Adelheid Kratzer et al.

JOURNAL OF LIPID RESEARCH (2009)

Article Biochemistry & Molecular Biology

LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse

Elaine M. Quinet et al.

JOURNAL OF LIPID RESEARCH (2009)

Review Biochemistry & Molecular Biology

Lipolysis and lipid mobilization in human adipose tissue

Max Lafontan et al.

PROGRESS IN LIPID RESEARCH (2009)

Article Cardiac & Cardiovascular Systems

Effect of niacin on LXRα and PPARγ expression and HDL-induced cholesterol efflux in adipocytes of hypercholesterolemic rabbits

Shui-ping Zhao et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2008)

Article Biochemistry & Molecular Biology

Activation of liver X receptors prevents statin-induced death of 3T3-L1 preadipocytes

Lise Madsen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Endocrinology & Metabolism

Hyperinsulinemia induces insulin resistance on glucose and lipid metabolism in a human adipocytic cell line:: Paracrine interaction with myocytes

Sonia Fernandez-Veledo et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)

Article Biochemistry & Molecular Biology

Liver X receptor α is a transcriptional repressor of the uncoupling protein 1 gene and the brown fat phenotype

Haibo Wang et al.

MOLECULAR AND CELLULAR BIOLOGY (2008)

Article Endocrinology & Metabolism

Selective partial agonism of liver X receptor α is related to differential corepressor recruitment

Caroline A. Phelan et al.

MOLECULAR ENDOCRINOLOGY (2008)

Article Endocrinology & Metabolism

Dissection of the insulin-sensitizing effect of liver X receptor ligands

S. Renee Commerford et al.

MOLECULAR ENDOCRINOLOGY (2007)

Article Biochemistry & Molecular Biology

SIRT1 deacetylates and positively regulates the nuclear receptor LXR

Xiaoling Li et al.

MOLECULAR CELL (2007)

Article Cardiac & Cardiovascular Systems

Liver X receptor activation potentiates the lipopolysaccharide response in human macrophages

Coralie Fontaine et al.

CIRCULATION RESEARCH (2007)

Article Biochemistry & Molecular Biology

SREBP-1-independent regulation of lipogenic gene expression in adipocytes

Motohiro Sekiya et al.

JOURNAL OF LIPID RESEARCH (2007)

Article Biochemistry & Molecular Biology

Molecular basis for repression of liver X receptor-mediated gene transcription by receptor-interacting protein 140

Tomas Jakobsson et al.

BIOCHEMICAL JOURNAL (2007)

Article Biochemistry & Molecular Biology

T0901317 is a potent PXR ligand: Implications for the biology ascribed to LXR

Nico Mitro et al.

FEBS LETTERS (2007)

Article Biochemistry & Molecular Biology

Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver

Takashi Yamamoto et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARγ

Serena Ghisletti et al.

MOLECULAR CELL (2007)

Article Biotechnology & Applied Microbiology

Liver X receptor gene polymorphisms and adipose tissue expression levels in obesity

Ingrid Dahlman et al.

PHARMACOGENETICS AND GENOMICS (2006)

Article Pharmacology & Pharmacy

The farnesoid X receptor promotes adipocyte differentiation and regulates adipose cell function in vivo

Giovanni Rizzo et al.

MOLECULAR PHARMACOLOGY (2006)

Article Biochemistry & Molecular Biology

Liver X receptor preferentially activates de novo lipogenesis in human preadipocytes

C Darimont et al.

BIOCHIMIE (2006)

Article Endocrinology & Metabolism

Hepatic peroxisomal fatty acid β-oxidation is regulated by liver X receptor α

TH Hu et al.

ENDOCRINOLOGY (2005)

Article Biochemistry & Molecular Biology

Identification and characterization of two alternatively spliced transcript variants of human liver X receptor alpha

MY Chen et al.

JOURNAL OF LIPID RESEARCH (2005)

Article Endocrinology & Metabolism

Differential effects of pharmacological liver X receptor activation on hepatic and peripheral insulin sensitivity in lean and ob/ob mice

A Grefhorst et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)

Article Endocrinology & Metabolism

Differential regulation of fatty acid elongation enzymes in brown adipocytes implies a unique role for Elovl3 during increased fatty acid oxidation

A Jakobsson et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)

Article Biochemistry & Molecular Biology

LXR is crucial in lipid metabolism

SM Ulven et al.

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2005)

Article Biochemistry & Molecular Biology

LXRβ is required for adipocyte growth, glucose homeostasis, and β cell function

I Gerin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Regulation of adipocyte differentiation and function by polyunsaturated fatty acids

L Madsen et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2005)

Article Cell Biology

LXRs regulate the balance between fat storage and oxidation

NY Kalaany et al.

CELL METABOLISM (2005)

Article Biochemistry & Molecular Biology

Transcription of the vascular endothelial growth factor gene in macrophages is regulated by liver X receptors

R Walczak et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Endocrinology & Metabolism

T0901317 is a dual LXR/FXR agonist

KA Houck et al.

MOLECULAR GENETICS AND METABOLISM (2004)

Article Biochemistry & Molecular Biology

Tissue-specific autoregulation of the LXRα gene facilitates induction of apoE in mouse adipose tissue

SM Ulven et al.

JOURNAL OF LIPID RESEARCH (2004)

Article Endocrinology & Metabolism

Gene expression profiling identifies liver X receptor alpha as an estrogen-regulated gene in mouse adipose tissue

L Lundholm et al.

JOURNAL OF MOLECULAR ENDOCRINOLOGY (2004)

Article Biochemistry & Molecular Biology

Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor α

KT Dalen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Gene expression profiling in adipose tissue indicates different transcriptional mechanisms of liver X receptors α and β, respectively

KR Steffensen et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)

Article Biochemistry & Molecular Biology

Regulation of ABCA1 expression and cholesterol efflux during adipose differentiation of 3T3-L1 cells

S Le Lay et al.

JOURNAL OF LIPID RESEARCH (2003)

Article Biochemistry & Molecular Biology

Substrate specificities of mouse heparan sulphate glucosaminyl 6-O-sulphotransferases

E Smeds et al.

BIOCHEMICAL JOURNAL (2003)

Article Endocrinology & Metabolism

Liver X receptors interact with corepressors to regulate gene expression

X Hu et al.

MOLECULAR ENDOCRINOLOGY (2003)

Article Multidisciplinary Sciences

Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue

BA Laffitte et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Biochemistry & Molecular Biology

Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages

A Castrillo et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

SB Joseph et al.

NATURE MEDICINE (2003)

Article Endocrinology & Metabolism

On the role of liver X receptors in lipid accumulation in adipocytes

LK Juvet et al.

MOLECULAR ENDOCRINOLOGY (2003)

Article Biochemistry & Molecular Biology

Antidiabetic action of a liver X receptor agonist mediated by inhibition of hepatic gluconeogenesis

GQ Cao et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Oxysterol-activated LXRα/RXR induces hSR-BI-promoter activity in hepatoma cells and preadipocytes

L Malerod et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)

Article Pharmacology & Pharmacy

Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue

TM Stulnig et al.

MOLECULAR PHARMACOLOGY (2002)

Article Multidisciplinary Sciences

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

SB Joseph et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Biochemistry & Molecular Biology

Different regulation of the LXRα promoter activity by isoforms of CCAAT/enhancer-binding proteins

KR Steffensen et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)

Article Chemistry, Medicinal

Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines

JL Collins et al.

JOURNAL OF MEDICINAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Autoregulation of the human liver X receptor α promoter

BA Laffitte et al.

MOLECULAR AND CELLULAR BIOLOGY (2001)

Article Medicine, Research & Experimental

Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRβ-deficient mice

S Alberti et al.

JOURNAL OF CLINICAL INVESTIGATION (2001)

Article Multidisciplinary Sciences

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

BA Laffitte et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

A Chawla et al.

MOLECULAR CELL (2001)

Article Cell Biology

Role of LXRs in control of lipogenesis

JR Schultz et al.

GENES & DEVELOPMENT (2000)

Article Multidisciplinary Sciences

LXRα functions as a cAMP-responsive transcriptional regulator of gene expression

K Tamura et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)