Journal
INTERNATIONAL JOURNAL OF OBESITY
Volume 35, Issue 7, Pages 883-890Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ijo.2011.96
Keywords
developmental programming; maternal obesity; insulin resistance; maternal diet
Categories
Funding
- Biotechnology and Biological Sciences Research Council [BB/F015364/1] Funding Source: Medline
- British Heart Foundation [FS/09/029/27902] Funding Source: Medline
- BBSRC [BB/F015364/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/F015364/1] Funding Source: researchfish
- British Heart Foundation [FS/09/029/27902] Funding Source: researchfish
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Obesity now represents one of the major health care issues of the 21st century. Its prevalence has increased exponentially in both the developed and developing world during the last couple of decades. Such a rapid rise can therefore not be explained by a change in genotype, but must result from environmental factors and their interaction with our genes. There is clear evidence to show that current environmental factors such as current diet and level of physical activity can influence our risk of obesity. However, there is growing evidence to suggest that factors acting during very early life can influence long-term energy balance. One such factor that is emerging as an important player is maternal obesity and/or over-nutrition during pregnancy and lactation. Early life may therefore represent a critical period during which intervention strategies could be developed to reduce the prevalence of obesity. International Journal of Obesity (2011) 35, 883-890; doi:10.1038/ijo.2011.96; published online 17 May 2011
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