Journal
INTERNATIONAL JOURNAL OF NEUROSCIENCE
Volume 119, Issue 5, Pages 743-752Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/00207450802325694
Keywords
goldfish; lens extraction; megalophthalmic; normal; optic nerve transection; retina
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A comparison in retinal degeneration was studied in the normal goldfish and the megalophthalmic goldfish after optic nerve transection or lens extraction by the TUNEL (Terminal transferase-mediated dUTP nick end labeling) technique. A significant number of TUNEL positive cells appeared in both cases 7 days after injury, with a more prominent result in the megalophthalmic eye. Lens extraction, had less apoptotic cell death in the experimental retinas.
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