Journal
INTERNATIONAL JOURNAL OF NANOMEDICINE
Volume 8, Issue -, Pages 413-420Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/IJN.S39456
Keywords
toxicity; glioma; apoptosis
Funding
- [NCN 2011/03/B/NZ9/03387]
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Graphene is a single atom-thick material with exciting potential. It can be used in many fields, from electronics to biomedicine. However, little is known about its toxicity and biocompatibility. Herein, we report a study on the toxicity of graphene platelets (GPs) by examining the influence of GPs on the morphology, mortality, viability, membrane integrity, and type of cell death of U87 and U118 glioma cells. It was found that graphene is toxic to glioma cells, but it activated apoptosis only in the U118 cell line, without inducing necrosis, indicating the potential applicability of GP in anticancer therapy.
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