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A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Autophagy is required for necrotic cell death in Caenorhabditis elegans
C. Samara et al.
CELL DEATH AND DIFFERENTIATION (2008)
CLOCK-mediated acetylation of BMAL1 controls circadian function
Jun Hirayama et al.
NATURE (2007)
Genetic links between diet and lifespan: shared mechanisms from yeast to humans
Nicholas A. Bishop et al.
NATURE REVIEWS GENETICS (2007)
Effects of a single dose of N-Acetyl-5-methoxytryptamine (Melatonin) and resistance exercise on the growth hormone/IGF-1 axis in young males and females
Erika Nassar et al.
JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION (2007)
Caloric restriction increases learning consolidation and facilitates synaptic plasticity through mechanisms dependent on NR2B Subunits of the NMDA receptor
Angela Fontan-Lozano et al.
JOURNAL OF NEUROSCIENCE (2007)
IKKβ suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway
Dung-Fang Lee et al.
CELL (2007)
Melatonin protects SK-N-SH neuroblastoma cells from amphetamine-induced neurotoxicity
Sirirat Klongpanichapak et al.
JOURNAL OF PINEAL RESEARCH (2007)
Dynamic FoxO transcription factors
Haojie Huang et al.
JOURNAL OF CELL SCIENCE (2007)
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
Dohoon Kim et al.
EMBO JOURNAL (2007)
Caloric restriction eliminates the aging-related decline in NMDA and AMPA receptor subunits in the rat hippocampus and induces homeostasis
Lei Shi et al.
EXPERIMENTAL NEUROLOGY (2007)
Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease
Veerendra Kumar Madald Halagappa et al.
NEUROBIOLOGY OF DISEASE (2007)
A sequence based synteny map between soybean and Arabidopsis thaliana
Jeffry L. Shultz et al.
BMC GENOMICS (2007)
Molecular circadian rhythms in central and peripheral clocks in mammals
Hugues Dardente et al.
CHRONOBIOLOGY INTERNATIONAL (2007)
One molecule, many derivatives: A never-ending interaction of melatonin with reactive oxygen and nitrogen species?
Dun-Xian Tan et al.
JOURNAL OF PINEAL RESEARCH (2007)
Autophagy genes protect against disease caused by polyglutamine expansion proteins in Caenorhabditis elegans
Kailiang Jia et al.
AUTOPHAGY (2007)
Resveratrol improves health and survival of mice on a high-calorie diet
Joseph A. Baur et al.
NATURE (2006)
Melatonin in cancer management: Progress and promise
Brittney Jung et al.
CANCER RESEARCH (2006)
NF-κB activation represses tumor necrosis factor-α-induced autophagy
Mojgan Djavaheri-Mergny et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Early aging and age-related pathologies in mice deficient in BMAL1, the core component of the circadian clock
Roman V. Kondratov et al.
GENES & DEVELOPMENT (2006)
C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span
Ala Berdichevsky et al.
CELL (2006)
Regulation of Intracellular Accumulation of Mutant Huntingtin by Beclin 1
Mamoru Shibata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Circadian regulator CLOCK is a histone acetyltransferase
Masao Doi et al.
CELL (2006)
A clock shock: Mouse CLOCK is not required for circadian oscillator function
Jason P. DeBruyne et al.
NEURON (2006)
Light during darkness and cancer: Relationships in circadian photoreception and tumor biology
SA Jasser et al.
CANCER CAUSES & CONTROL (2006)
Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions
JRA Ripperger et al.
NATURE GENETICS (2006)
The circadian clock within the heart: potential influence on myocardial gene expression, metabolism, and function
ME Young
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)
Autophagy in neurodegenerative disease: friend, foe or turncoat?
Ralph A. Nixon
TRENDS IN NEUROSCIENCES (2006)
Immunocytochemical demonstration of day/night changes of clock gene protein levels in the murine adrenal gland: differences between melatonin-proficient (C3H) and melatonin-deficient (C57BL) mice
C Torres-Farfan et al.
JOURNAL OF PINEAL RESEARCH (2006)
Sustained activation of Akt by melatonin contributes to the protection against kainic acid-induced neuronal death in hippocampus
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JOURNAL OF PINEAL RESEARCH (2006)
Aspects of growth hormone and insulin-like growth factor-I related to neuroprotection, regeneration, and functional plasticity in the adult brain
N. David Aberg et al.
THESCIENTIFICWORLDJOURNAL (2006)
SIRT1 protects against microglia-dependent amyloid-β toxicity through inhibiting NF-κB signaling
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
M Kaeberlein et al.
SCIENCE (2005)
New twist on neuronal insulin receptor signaling in health, disease, and therapeutics
A Wada et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2005)
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
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CELL (2005)
Melatonin, aging, and age-related diseases - Perspectives for prevention, intervention, and therapy
B Poeggeler
ENDOCRINE (2005)
Local expression of GH and IGF-1 in the hippocampus of GH-deficient long-lived mice
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NEUROBIOLOGY OF AGING (2005)
Circadian regulation of hippocampal long-term potentiation
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JOURNAL OF BIOLOGICAL RHYTHMS (2005)
The human pineal gland and melatonin in aging and Alzheimer's disease
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JOURNAL OF PINEAL RESEARCH (2005)
System-level identification of transcriptional circuits underlying mammalian circadian clocks
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NATURE GENETICS (2005)
Interactions between melatonin and nicotinamide nucleotide: NADH preservation in cells and in cell-free systems by melatonin
DX Tan et al.
JOURNAL OF PINEAL RESEARCH (2005)
Dysregulation of the TSC-mTOR pathway in human disease
K Inoki et al.
NATURE GENETICS (2005)
Development by self-digestion: Molecular mechanisms and biological functions of autophagy
B Levine et al.
DEVELOPMENTAL CELL (2004)
Posttranscriptional and posttranslational regulation of clock genes
E Harms et al.
JOURNAL OF BIOLOGICAL RHYTHMS (2004)
A functional genomics strategy reveals rora as a component of the mammalian circadian clock
TK Sato et al.
NEURON (2004)
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
S Shimizu et al.
NATURE CELL BIOLOGY (2004)
Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
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EMBO JOURNAL (2004)
Melatonin, human aging, and age-related diseases
M Karasek
EXPERIMENTAL GERONTOLOGY (2004)
The emerging role of epigenetics in cellular and organismal aging
D Bandyopadhyay et al.
EXPERIMENTAL GERONTOLOGY (2003)
Calorie restriction reduces pinealectomy-induced insulin resistance by improving GLUT4 gene expression and its translocation to the plasma membrane
MM Zanquetta et al.
JOURNAL OF PINEAL RESEARCH (2003)
Melatonin effect on rat body weight regulation in response to high-fat diet at middle age
SS Puchalski et al.
ENDOCRINE (2003)
Genetics and the specificity of the aging process
S Hekimi et al.
SCIENCE (2003)
Rhythmic histone acetylation underlies transcription in the mammalian circadian clock
JP Etchegaray et al.
NATURE (2003)
The pineal gland is critical for circadian Period1 expression in the striatum and for circadian cocaine sensitization in mice
T Uz et al.
NEUROPSYCHOPHARMACOLOGY (2003)
Effect of pinealectomy on plasma levels of insulin and leptin and on hepatic lipids in type 2 diabetic rats
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JOURNAL OF PINEAL RESEARCH (2003)
The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo
LN Fu et al.
CELL (2002)
Coordination of circadian timing in mammals
SM Reppert et al.
NATURE (2002)
The orphan nuclear receptor REV-ERBα controls circadian transcription within the positive limb of the mammalian circadian oscillator
N Preitner et al.
CELL (2002)
Medicine - The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
J Hardy et al.
SCIENCE (2002)
Redox potential: Differential roles in dCRY and mCRY1 functions
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CURRENT BIOLOGY (2002)
Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice
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JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2002)
Leptin signaling and aging: insight from caloric restriction
I Shimokawa et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2001)
Light induces chromatin modification in cells of the mammalian circadian clock
C Crosio et al.
NATURE NEUROSCIENCE (2000)
Age-dependent changes of the circadian system
D Weinert
CHRONOBIOLOGY INTERNATIONAL (2000)