Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 15, Issue 9, Pages 16511-16521Publisher
MDPI AG
DOI: 10.3390/ijms150916511
Keywords
sponge; Petrosia; polyacetylene
Funding
- National Museum of Marine Biology and Aquarium
- Ministry of Science and Technology (MOST) [103-2320-B-291-001-MY3]
- CMU under Aim for Top University Plan of the Ministry of Education, Taiwan
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The sponge Petrosia sp. yielded five polyacetylenic compounds (1-5), including two new polyacetylenes, petrosianynes A (1) and B (2). The structures of these compounds were elucidated by detailed spectroscopic analysis and by comparison with the physical and spectral data of related known analogues. Compounds 1-5 exhibited significant cytotoxic activity against a limited panel of cancer cell lines.
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