4.7 Review

Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Maturation of autophagosomes and endosomes: A key role for Rab7

Juha M. T. Hyttinen et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)

Article Biochemistry & Molecular Biology

Impaired SIRT1 nucleocytoplasmic shuttling in the senescent heart during ischemic stress

Chao Tong et al.

FASEB JOURNAL (2013)

Article Geriatrics & Gerontology

Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity

Jae-Kyo Jeong et al.

NEUROBIOLOGY OF AGING (2013)

Article Cell Biology

Inflammaging: disturbed interplay between autophagy and inflammasomes

Antero Salminen et al.

AGING-US (2012)

Review Biochemistry & Molecular Biology

Redox Regulation of p53, Redox Effectors Regulated by p53: A Subtle Balance

Agnes Maillet et al.

ANTIOXIDANTS & REDOX SIGNALING (2012)

Review Biochemistry & Molecular Biology

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

Jisun Lee et al.

BIOCHEMICAL JOURNAL (2012)

Review Biochemistry & Molecular Biology

Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases

Antero Salminen et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2012)

Review Food Science & Technology

Antioxidants in Food: Mere Myth or Magic Medicine?

R. G. Berger et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2012)

Review Geriatrics & Gerontology

Stress Resistance in the Naked Mole-Rat: The Bare Essentials - A Mini-Review

Kaitlyn N. Lewis et al.

GERONTOLOGY (2012)

Article Biochemistry & Molecular Biology

Effect of microRNA-34a in cell cycle, differentiation, and apoptosis: A review

Fei Chen et al.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2012)

Article Cell Biology

Redox implications of AMPK-mediated signal transduction beyond energetic clues

Simone Cardaci et al.

JOURNAL OF CELL SCIENCE (2012)

Article Biochemistry & Molecular Biology

AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1

Anthony M. J. Sanchez et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2012)

Article Multidisciplinary Sciences

The sirtuin SIRT6 regulates lifespan in male mice

Yariv Kanfi et al.

NATURE (2012)

Review Biotechnology & Applied Microbiology

Are sirtuins viable targets for improving healthspan and lifespan?

Joseph A. Baur et al.

NATURE REVIEWS DRUG DISCOVERY (2012)

Review Cell Biology

Sirtuins as regulators of metabolism and healthspan

Riekelt H. Houtkooper et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)

Article Cell Biology

Protein Oxidative Damage at the Crossroads of Cellular Senescence, Aging, and Age-Related Diseases

Martin A. Baraibar et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)

Review Cell Biology

The Neglected Significance of Antioxidative Stress

B. Poljsak et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)

Article Multidisciplinary Sciences

Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1

Weijing Cai et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

Keap1 degradation by autophagy for the maintenance of redox homeostasis

Keiko Taguchi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

Superoxide dismutase is dispensable for normal animal lifespan

Jeremy Michael Van Raamsdonk et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Biochemistry & Molecular Biology

Nuclear factor-κB, p53, and mitochondria: regulation of cellular metabolism and the Warburg effect

Renee F. Johnson et al.

TRENDS IN BIOCHEMICAL SCIENCES (2012)

Review Biochemistry & Molecular Biology

Mitochondrial uncoupling protein 2 (UCP2) in glucose and lipid metabolism

Sabrina Diano et al.

TRENDS IN MOLECULAR MEDICINE (2012)

Review Cell Biology

Protein homeostasis and aging: The importance of exquisite quality control

Hiroshi Koga et al.

AGEING RESEARCH REVIEWS (2011)

Article Nutrition & Dietetics

Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis

Pablo J. Fernandez-Marcos et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2011)

Article Cardiac & Cardiovascular Systems

SIRT1-mediated acute cardioprotection

Sergiy M. Nadtochiy et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2011)

Review Biochemistry & Molecular Biology

Oxidative Stress as Pathogenesis of Cardiovascular Risk Associated with Metabolic Syndrome

Hajime Otani

ANTIOXIDANTS & REDOX SIGNALING (2011)

Article Biochemistry & Molecular Biology

Interaction of p53 with Tumor Suppressive and Oncogenic Signaling Pathways to Control Cellular Reactive Oxygen Species Production

Maria Fatima Ladelfa et al.

ANTIOXIDANTS & REDOX SIGNALING (2011)

Review Biochemistry & Molecular Biology

Autophagy Signaling Through Reactive Oxygen Species

Ju Huang et al.

ANTIOXIDANTS & REDOX SIGNALING (2011)

Review Nutrition & Dietetics

Deacetylation of PGC-1α by SIRT1: importance for skeletal muscle function and exercise-induced mitochondrial biogenesis

Brendon J. Gurd

APPLIED PHYSIOLOGY NUTRITION AND METABOLISM (2011)

Review Biochemistry & Molecular Biology

Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network

Richard C. Scarpulla

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)

Review Biochemistry & Molecular Biology

Autophagy: Renovation of Cells and Tissues

Noboru Mizushima et al.

Review Cell Biology

Crosstalk of reactive oxygen species and NF-kappa B signaling

Michael J. Morgan et al.

CELL RESEARCH (2011)

Article Endocrinology & Metabolism

SirT1 Regulates Adipose Tissue Inflammation

Matthew P. Gillum et al.

DIABETES (2011)

Article Geriatrics & Gerontology

Autophagy regulates ROS-induced cellular senescence via p21 in a p38 MAPKα dependent manner

Yi Luo et al.

EXPERIMENTAL GERONTOLOGY (2011)

Article Geriatrics & Gerontology

Regulation of Drosophila lifespan by JNK signaling

Benoit Biteau et al.

EXPERIMENTAL GERONTOLOGY (2011)

Review Biochemistry & Molecular Biology

Beyond ATM: The protein kinase landscape of the DNA damage response

Ariel Bensimon et al.

FEBS LETTERS (2011)

Review Biochemistry & Molecular Biology

Uncoupling proteins and the control of mitochondrial reactive oxygen species production

Ryan J. Mailloux et al.

FREE RADICAL BIOLOGY AND MEDICINE (2011)

Review Biochemistry & Molecular Biology

Extending life span by increasing oxidative stress

Michael Ristow et al.

FREE RADICAL BIOLOGY AND MEDICINE (2011)

Article Cell Biology

JNK regulates FoxO-dependent autophagy in neurons

Ping Xu et al.

GENES & DEVELOPMENT (2011)

Review Immunology

The inflammasome: an integrated view

Olaf Gross et al.

IMMUNOLOGICAL REVIEWS (2011)

Article Biochemistry & Molecular Biology

FoxO1 Mediates an Autofeedback Loop Regulating SIRT1 Expression

Shiqin Xiong et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

FoxO Transcription Factors Promote Cardiomyocyte Survival upon Induction of Oxidative Stress

Arunima Sengupta et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

NAD+-dependent SIRT1 Deacetylase Participates in Epigenetic Reprogramming during Endotoxin Tolerance

Tie Fu Liu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Review Biotechnology & Applied Microbiology

Sirtuins: Molecular Traffic Lights in the Crossroad of Oxidative Stress, Chromatin Remodeling, and Transcription

Ramkumar Rajendran et al.

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2011)

Article Cardiac & Cardiovascular Systems

Constitutive SIRT1 overexpression impairs mitochondria and reduces cardiac function in mice

Tsuneaki Kawashima et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2011)

Review Genetics & Heredity

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

Antero Salminen et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2011)

Review Biochemical Research Methods

Oxidative stress, inflamm-aging and immunosenescence

Elvira S. Cannizzo et al.

JOURNAL OF PROTEOMICS (2011)

Article Urology & Nephrology

miR-335 and miR-34a Promote Renal Senescence by Suppressing Mitochondrial Antioxidative Enzymes

Xue-Yuan Bai et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2011)

Article Biochemistry & Molecular Biology

Hypoxia Triggers AMPK Activation through Reactive Oxygen Species-Mediated Activation of Calcium Release-Activated Calcium Channels

Paul T. Mungai et al.

MOLECULAR AND CELLULAR BIOLOGY (2011)

Article Biochemistry & Molecular Biology

The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD+

Zachary Gerhart-Hines et al.

MOLECULAR CELL (2011)

Article Biochemistry & Molecular Biology

Complex Inhibitory Effects of Nitric Oxide on Autophagy

Sovan Sarkar et al.

MOLECULAR CELL (2011)

Article Multidisciplinary Sciences

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

Camilla Burnett et al.

NATURE (2011)

Review Medicine, General & Internal

Sirtuins, Aging, and Medicine

Leonard Guarente

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Review Biology

The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing

Cynthia Kenyon

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2011)

Review Multidisciplinary Sciences

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

Douglas R. Green et al.

SCIENCE (2011)

Review Biochemistry & Molecular Biology

Regulation of autophagy by ROS: physiology and pathology

Ruth Scherz-Shouval et al.

TRENDS IN BIOCHEMICAL SCIENCES (2011)

Review Biochemistry & Molecular Biology

Chromatin regulation and genome maintenance by mammalian SIRT6

Ruth I. Tennen et al.

TRENDS IN BIOCHEMICAL SCIENCES (2011)

Review Cardiac & Cardiovascular Systems

Protection of the Heart Against Ischemia/Reperfusion by Silent Information Regulator 1

Takanobu Yamamoto et al.

TRENDS IN CARDIOVASCULAR MEDICINE (2011)

Review Cell Biology

Taking a good look at free radicals in the aging process

Siegfried Hekimi et al.

TRENDS IN CELL BIOLOGY (2011)

Review Endocrinology & Metabolism

Pleiotropic effects of growth hormone signaling in aging

Andrzej Bartke

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2011)

Review Cell Biology

Hydrogen peroxide: a Jekyll and Hyde signalling molecule

D. R. Gough et al.

CELL DEATH & DISEASE (2011)

Article Cell Biology

p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting

J. M. McClung et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2010)

Review Pathology

Mammalian Sirtuins: Biological Insights and Disease Relevance

Marcia C. Haigis et al.

ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)

Article Biochemistry & Molecular Biology

Redox Regulation of Sirtuin-1 by S-Glutathiolation

Rebecca S. Zee et al.

ANTIOXIDANTS & REDOX SIGNALING (2010)

Article Biochemistry & Molecular Biology

Reactive Oxygen Species and Aging in Caenorhabditis elegans: Causal or Casual Relationship?

Jeremy Michael Van Raamsdonk et al.

ANTIOXIDANTS & REDOX SIGNALING (2010)

Article Biochemistry & Molecular Biology

Transcriptional regulation of NADPH oxidase isoforms, Nox1 and Nox4, by nuclear factor-κB in human aortic smooth muscle cells

Adrian Manea et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)

Article Biochemistry & Molecular Biology

MicroRNA-34a regulation of endothelial senescence

Takashi Ito et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)

Review Cell Biology

Insulin/IGF-1 paradox of aging: Regulation via AKT/IKK/NF-κB signaling

Antero Salminen et al.

CELLULAR SIGNALLING (2010)

Article Cardiac & Cardiovascular Systems

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

Nirmala Hariharan et al.

CIRCULATION RESEARCH (2010)

Article Biochemistry & Molecular Biology

Exposure to Hydrogen Peroxide Induces Oxidation and Activation of AMP-activated Protein Kinase

Jaroslaw W. Zmijewski et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Cell Biology

GAPDH mediates nitrosylation of nuclear proteins

Michael D. Kornberg et al.

NATURE CELL BIOLOGY (2010)

Article Multidisciplinary Sciences

The Association of AMPK with ULK1 Regulates Autophagy

Jong Woo Lee et al.

PLOS ONE (2010)

Article Multidisciplinary Sciences

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

Angela Alexander et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

ATM Activation by Oxidative Stress

Zhi Guo et al.

SCIENCE (2010)

Review Biochemistry & Molecular Biology

Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes

Robert B. Hamanaka et al.

TRENDS IN BIOCHEMICAL SCIENCES (2010)

Article Endocrinology & Metabolism

Uncoupling protein-2 regulates lifespan in mice

Zane B. Andrews et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)

Review Immunology

Regulation and Function of NF-kappa B Transcription Factors in the Immune System

Sivakumar Vallabhapurapu et al.

ANNUAL REVIEW OF IMMUNOLOGY (2009)

Article Biochemistry & Molecular Biology

Upregulation of Beclin-1 expression and phosphorylation of Bcl-2 and p53 are involved in the JNK-mediated autophagic cell death

Kyung-Jin Park et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)

Review Biochemistry & Molecular Biology

How mitochondria produce reactive oxygen species

Michael P. Murphy

BIOCHEMICAL JOURNAL (2009)

Article Biochemical Research Methods

Meta-analysis of age-related gene expression profiles identifies common signatures of aging

Joao Pedro de Magalhaes et al.

BIOINFORMATICS (2009)

Article Biochemistry & Molecular Biology

Superoxide is the major reactive oxygen species regulating autophagy

Y. Chen et al.

CELL DEATH AND DIFFERENTIATION (2009)

Review Cell Biology

SIRT1: Regulation of longevity via autophagy

Antero Salminen et al.

CELLULAR SIGNALLING (2009)

Review Biochemistry & Molecular Biology

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

Carles Canto et al.

CURRENT OPINION IN LIPIDOLOGY (2009)

Article Biochemistry & Molecular Biology

Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio

Brooke M. Emerling et al.

FREE RADICAL BIOLOGY AND MEDICINE (2009)

Article Immunology

NF-κB Signaling in the Aging Process

Antero Salminen et al.

JOURNAL OF CLINICAL IMMUNOLOGY (2009)

Review Cell Biology

Hormonal control of aging in rodents: The somatotropic axis

Holly M. Brown-Borg

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2009)

Article Cell Biology

Insulin exhibits short-term anti-inflammatory but long-term proinflammatory effects in vitro

Yasumasa Iwasaki et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2009)

Article Multidisciplinary Sciences

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Carles Canto et al.

NATURE (2009)

Article Multidisciplinary Sciences

JNK1 Phosphorylates SIRT1 and Promotes Its Enzymatic Activity

Nargis Nasrin et al.

PLOS ONE (2009)

Review Biochemistry & Molecular Biology

Regulation of the aging process by autophagy

Antero Salminen et al.

TRENDS IN MOLECULAR MEDICINE (2009)

Article Genetics & Heredity

Deletion of the Mitochondrial Superoxide Dismutase sod-2 Extends Lifespan in Caenorhabditis elegans

Jeremy M. Van Raamsdonk et al.

PLOS GENETICS (2009)

Article Critical Care Medicine

SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease

Saravanan Rajendrasozhan et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2008)

Review Biochemistry & Molecular Biology

Terpenoids: natural inhibitors of NF-kappa B signaling with anti-inflammatory and anticancer potential

A. Salminen et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2008)

Review Biochemistry & Molecular Biology

ROS and p53: A versatile partnership

Bin Liu et al.

FREE RADICAL BIOLOGY AND MEDICINE (2008)

Review Physiology

Inflammation and endothelial dysfunction during aging: role of NF-kappa B

Anna Csiszar et al.

JOURNAL OF APPLIED PHYSIOLOGY (2008)

Review Physiology

Negligible senescence in the longest living rodent, the naked mole-rat: insights from a successfully aging species

Rochelle Buffenstein

JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMS AND ENVIRONMENTAL PHYSIOLOGY (2008)

Article Biochemistry & Molecular Biology

JNK1-mediated phosphorylation of BcI-2 regulates starvation-induced autophagy

Yongjie Wei et al.

MOLECULAR CELL (2008)

Article Multidisciplinary Sciences

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

In Hye Lee et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

miR-34a repression of SIRT1 regulates apoptosis

Munekazu Yamakuchi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Genetics & Heredity

Autophagy and aging: keeping that old broom working

Ana Maria Cuervo

TRENDS IN GENETICS (2008)

Article Cell Biology

Motif module map reveals enforcement of aging by continual NF-κB activity

Adam S. Adler et al.

GENES & DEVELOPMENT (2007)

Article Cell Biology

FoxO3 controls autophagy in skeletal muscle in vivo

Cristina Mammucari et al.

CELL METABOLISM (2007)

Article Biochemistry & Molecular Biology

SIRT1 is involved in glucocorticoid-mediated control of uncoupling protein-3 gene transcription

Ramon Amat et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation

Jiandi Zhang

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Physiology

Life and death: Metabolic rate, membrane composition, and life span of animals

A. J. Hulbert et al.

PHYSIOLOGICAL REVIEWS (2007)

Article Cardiac & Cardiovascular Systems

Sirt1 regulates aging and resistance to oxidative stress in the heart

Ralph R. Alcendor et al.

CIRCULATION RESEARCH (2007)

Article Biochemistry & Molecular Biology

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

Ruth Scherz-Shouval et al.

EMBO JOURNAL (2007)

Article Geriatrics & Gerontology

Genetic control of longevity in C-elegans

Bart P. Braeckman et al.

EXPERIMENTAL GERONTOLOGY (2007)

Article Geriatrics & Gerontology

The neuroprotective effects of a locally acting IGF-1 isoform

Antonio Musaro et al.

EXPERIMENTAL GERONTOLOGY (2007)

Review Cell Biology

Integrating cell-signalling pathways with NF-kappa B and IKK function

Neil D. Perkins

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)

Review Pharmacology & Pharmacy

NF-κB activation by reactive oxygen species:: Fifteen years later

Geoffrey Gloire et al.

BIOCHEMICAL PHARMACOLOGY (2006)

Article Pharmacology & Pharmacy

Regulation of inflammation and redox signaling by dietary polyphenols

Irfan Rahman et al.

BIOCHEMICAL PHARMACOLOGY (2006)

Review Biochemistry & Molecular Biology

Sirtuins in aging and age-related disease

Valter D. Longo et al.

Article Biochemistry & Molecular Biology

NF-κB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox

J Anrather et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic β cells

L Bordone et al.

PLOS BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

R Mostoslavsky et al.

Article Multidisciplinary Sciences

Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production

A Trifunovic et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Sir2 blocks extreme life-span extension

P Fabrizio et al.

Review Biochemistry & Molecular Biology

Functions and mechanisms of redox regulation of cysteine-based phosphatases

A Salmeen et al.

ANTIOXIDANTS & REDOX SIGNALING (2005)

Article Biochemistry & Molecular Biology

SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1α

S Nemoto et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Multidisciplinary Sciences

Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1

JT Rodgers et al.

NATURE (2005)

Article Biochemistry & Molecular Biology

IKK-β links inflammation to obesity-induced insulin resistance

MC Arkan et al.

NATURE MEDICINE (2005)

Review Biochemistry & Molecular Biology

The ASK1-MAP kinase cascades in mammalian stress response

J Matsukawa et al.

JOURNAL OF BIOCHEMISTRY (2004)

Article Multidisciplinary Sciences

An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster

JH Bauer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2SIRT1

A van der Horst et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Multidisciplinary Sciences

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

B Rogina et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase

F Yeung et al.

EMBO JOURNAL (2004)

Review Biochemistry & Molecular Biology

The Sir2 family of protein deacetylases

G Blander et al.

ANNUAL REVIEW OF BIOCHEMISTRY (2004)

Article Multidisciplinary Sciences

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

KT Howitz et al.

NATURE (2003)

Article Cell Biology

Stress resistance as a determinate of C-elegans lifespan

GJ Lithgow et al.

MECHANISMS OF AGEING AND DEVELOPMENT (2002)

Review Immunology

NF-kappa B at the crossroads of life and death

M Karin et al.

NATURE IMMUNOLOGY (2002)

Article Multidisciplinary Sciences

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

HA Tissenbaum et al.

NATURE (2001)

Article Biochemistry & Molecular Biology

Characterization of aging-associated up-regulation of constitutive nuclear factor-κB binding activity

M Helenius et al.

ANTIOXIDANTS & REDOX SIGNALING (2001)

Article Biochemistry & Molecular Biology

Mitochondrial free radical generation, oxidative stress, and aging

E Cadenas et al.

FREE RADICAL BIOLOGY AND MEDICINE (2000)

Article Biochemistry & Molecular Biology

Energy metabolism in uncoupling protein 3 gene knockout mice

AJ Vidal-Puig et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Review Food Science & Technology

A comprehensive overview of the complex relationship between epigenetics, bioactive components, cancer, and aging

Sule Kocabas et al.

Summary: Epigenetic modifications, nutritional components, and their impact on gene expression play crucial roles in cancer and aging, which can be altered by adjusting dietary habits.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION