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The Clinical Utilization of Circulating Cell Free DNA (CCFDNA) in Blood of Cancer Patients

Journal

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 14, Issue 9, Pages 18925-18958

Publisher

MDPI
DOI: 10.3390/ijms140918925

Keywords

circulating cell free DNA; neoplasms; early diagnosis; follow up on cancer treatment; prognosis

Funding

  1. NIH/NCI [U56CA101599, CA15083-25S3, U54CA14393]

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Qualitative and quantitative testing of circulating cell free DNA (CCFDNA) can be applied for the management of malignant and benign neoplasms. Detecting circulating DNA in cancer patients may help develop a DNA profile for early stage diagnosis in malignancies. The technical issues of obtaining, using, and analyzing CCFDNA from blood will be discussed.

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