4.7 Article

Cladieunicellins K and L, New Eunicellin-Based Diterpenoids from an Octocoral Cladiella sp.

Journal

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 14, Issue 11, Pages 21781-21789

Publisher

MDPI AG
DOI: 10.3390/ijms141121781

Keywords

eunicellin; Cladiella; cladieunicellin; cytotoxicity

Funding

  1. National Dong Hwa University
  2. National Museum of Marine Biology and Aquarium
  3. Asia-Pacific Ocean Research Center, National Sun Yat-sen University
  4. National Science Council, Taiwan [NSC 102-2325-B-291-001, 101-2320-B-291-001-MY3]

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Two new eunicellin-based diterpenoids, cladieunicellins K (1) and L (2), were isolated from an octocoral Cladiella sp. The structures of 1 and 2 were elucidated by spectroscopic methods and 2 exhibited moderate cytotoxicity towards the MOLT-4 human leukemia.

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