Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 9, Issue 5, Pages 864-871Publisher
MDPI AG
DOI: 10.3390/ijms9050864
Keywords
ionic liquid type photosensitizers; choline; purpurin-18; cholinium-purpurin-18; gold nanoparticles; anticancer agents
Funding
- National Research Foundation of Korea [과C6B2608] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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For possible future use in Photodynamic Therapy (PDT) and/or Photothermal Therapy (PTT) of cancer and screening of cancer cells a new type of ionic liquid photosensitizer -Cholinium-Purpurin-18 (Chol-Pu-18) - was synthesized and small gold (Au) nanoparticles, stabilized by this photosensitizer were prepared without adding any particular reducing agents and CTAB. UV-Vis spectroscopy and Transmission Electron Microscopy (TEM) were used for characterization of the nanoparticles and FAB-MS and NMR of the ionic liquid choline hydroxide, purpurin carboxylate and their ionic liquid type of photosensitizer were obtained.
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