Journal
INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH
Volume 20, Issue 1, Pages 40-49Publisher
WILEY
DOI: 10.1002/mpr.329
Keywords
missing data; multiple imputation; analyze
Categories
Funding
- National Institute of Mental Health [1R01MH075828-01A1]
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Multivariate imputation by chained equations (MICE) has emerged as a principled method of dealing with missing data. Despite properties that make MICE particularly useful for large imputation procedures and advances in software development that now make it accessible to many researchers, many psychiatric researchers have not been trained in these methods and few practical resources exist to guide researchers in the implementation of this technique. This paper provides an introduction to the MICE method with a focus on practical aspects and challenges in using this method. A brief review of software programs available to implement MICE and then analyze multiply imputed data is also provided. Copyright (C) 2011 John Wiley & Sons, Ltd.
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