Journal
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
Volume 370, Issue -, Pages 75-95Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijms.2014.06.016
Keywords
Ion mobility; Mass spectrometry; Instrumentation; Modeling; Bio-macromolecules; Structure
Funding
- National Science Foundation (USA)
- US Air Force Office of Scientific Research
- National Institute on Aging of the National Institutes of Health
- NSF [CHE-1301032]
- AFOSR [FA9550-11-1-0113, FA2386-12-1-3011]
- NIH [AG047116-01]
- Direct For Mathematical & Physical Scien [1301032] Funding Source: National Science Foundation
- Division Of Chemistry [1301032] Funding Source: National Science Foundation
Ask authors/readers for more resources
Ion mobility is not a newly discovered phenomenon. It has roots going back to Langevin at the beginning of the 20th century. Our group initially got involved by accident around 1990 and this paper is a brief account of what has transpired here at UCSB the past 25 years in response to this happy accident. We started small, literally, with transition metal atomic ions and transitioned to carbon clusters, synthetic polymers, most types of biological molecules and eventually peptide and protein oligomeric assembly. Along the way we designed and built several generations of instruments, a process that is still ongoing. And perhaps most importantly we have incorporated theory with experiment from the beginning; a necessary wedding that allows an atomistic face to be put on the otherwise interesting but not fully informative cross section measurements. (C) 2014 Elsevier B.V. All rights reserved.
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