Journal
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Volume 14, Issue 12, Pages E1040-E1047Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.ijid.2010.08.005
Keywords
Aspergillus; Endocarditis; Fungal; Culture-negative endocarditis
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We present a case of cardiac device-related Aspergillus endocarditis in a patient with a pacemaker and an allogeneic bone marrow transplant to segue into a review of the Aspergillus endocarditis literature. Aspergillus endocarditis should be suspected in patients with underlying immunosuppression, negative cultures, and a vegetation on echocardiography. Diagnosis ultimately requires confirmation by tissue histology and culture. The optimal treatment approach often requires aggressive surgical debridement in conjunction with prolonged antifungal therapy. (C) 2010 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
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