Journal
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
Volume 14, Issue 11, Pages E1018-E1019Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.ijid.2010.08.001
Keywords
Colistin; Aerosol; Pneumonitis; Hypersensitive; Resistance
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We report a case of hypersensitivity pneumonitis, possibly due to aerosolized colistin therapy for severe multi-resistant Gram-negative pneumonia. Microbiological eradication was achieved with colistin therapy, which was stopped after 12 days in view of rising eosinophilia and possible lung fibrosis. The eosinophil count started to normalize 3 days after stopping colistin therapy and the patient was eventually weaned to minimal ventilatory support. (C) 2010 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
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