Journal
INTERNATIONAL JOURNAL OF HYPERTHERMIA
Volume 29, Issue 6, Pages 590-597Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/02656736.2013.807438
Keywords
Electrical conductivity; radiofrequency ablation; thermal conductivity; theoretical modelling; tissue characteristics
Funding
- Spanish Plan Nacional de I+D+I del Ministerio de Ciencia e Innovacion [TEC2011-27133-C02-01]
- UPV [PAID-06-11]
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Purpose: Although theoretical modelling is widely used to study different aspects of radiofrequency ablation (RFA), its utility is directly related to its realism. An important factor in this realism is the use of mathematical functions to model the temperature dependence of thermal (k) and electrical (sigma) conductivities of tissue. Our aim was to review the piecewise mathematical functions most commonly used for modelling the temperature dependence of k and sigma in RFA computational modelling. Materials and methods: We built a hepatic RFA theoretical model of a cooled electrode and compared lesion dimensions and impedance evolution with combinations of mathematical functions proposed in previous studies. We employed the thermal damage contour D63 to compute the lesion dimension contour, which corresponds to Omega = 1, Omega being local thermal damage assessed by the Arrhenius damage model. Results: The results were very similar in all cases in terms of impedance evolution and lesion size after 6 min of ablation. Although the relative differences between cases in terms of time to first roll-off (abrupt increase in impedance) were as much as 12%, the maximum relative differences in terms of the short lesion (transverse) diameter were below 3.5%. Conclusions: The findings suggest that the different methods of modelling temperature dependence of k and sigma reported in the literature do not significantly affect the computed lesion diameter.
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