Journal
INTERNATIONAL JOURNAL OF HIGH PERFORMANCE COMPUTING APPLICATIONS
Volume 23, Issue 3, Pages 252-264Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/1094342009106192
Keywords
integrative biomedical research; system level integrative analysis; multi-scale integrative investigation
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Funding
- NHLBI NIH HHS [R24 HL085343, R24 HL085343-01A1] Funding Source: Medline
- NLM NIH HHS [R01 LM009239, R01 LM009239-01A1] Funding Source: Medline
- Division Of Computer and Network Systems
- Direct For Computer & Info Scie & Enginr [0917775] Funding Source: National Science Foundation
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Integrative biomedical research projects query, analyze, and integrate many different data types and make use of datasets obtained from measurements or simulations of structure and function at multiple biological scales. With the increasing availability of high-throughput and high-resolution instruments, the integrative biomedical research imposes many challenging requirements on software middleware systems. In this paper, we look at some of these requirements using example research pattern templates. We then discuss how middleware systems, which incorporate Grid and high-performance computing, could be employed to address the requirements.
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