Journal
MICROBES AND INFECTION
Volume 17, Issue 7, Pages 473-483Publisher
ELSEVIER
DOI: 10.1016/j.micinf.2015.03.007
Keywords
Oral microbes; Porphyromonas gingivalis; Fusobacterium nucleatum; Cancer; Chronic diseases; Small molecule danger signaling
Categories
Funding
- NIDCR grant [R01DE016593]
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Associations between oral and systemic health are ancient. Oral opportunistic bacteria, particularly, Porphyromonas gingivalis and Fusobacterium nucleatum, have recently been deviated from their traditional roles as periodontal pathogens and arguably ascended to central players based on their participations in complex co-dependent mechanisms of diverse systemic chronic diseases risk and pathogenesis, including cancers, rheumatoid-arthritis, and diabetes. (C) 2015 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.
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