4.5 Article

Effects of a soybean nutrition bar on the postprandial blood glucose and lipid levels in patients with diabetes mellitus

Journal

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.3109/09637486.2012.694847

Keywords

glycaemic index; soy; diabetes mellitus; postprandial hyperglycaemia

Funding

  1. Otsuka Pharmaceutical Co. Ltd.

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We investigated the influence of a soybean nutrition bar made from whole soy powder on the blood glucose, insulin and lipid levels in comparison with a test cookie with the same amount of energy in patients with diabetes mellitus. In the cross-over designed study, meal tolerance tests using the soybean nutrition bar and test cookie were performed. Two kinds of test meals were used: Study 1 80 kcal, Study 2 592 kcal. The blood glucose response was significantly lower in the soybean nutrition bar trial than in the cookie trial (Studies 1 and 2, p < 0.001). The blood insulin response was also significantly lower in the soybean nutrition bar trial than in the cookie trial (Study 2, p < 0.001). The blood triglyceride and non-esterified fatty acid responses were not significantly different between the two trials, nor were the changes in breath H-2 enrichment (Study 2). The soybean nutrition bar did not induce postprandial hyperglycaemia in diabetic patients unlike the isoenergetic test cookies.

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