Cost-of-illness studies and cost-effectiveness analyses in eating disorders: A systematic review

Objective: To review cost-of-illness studies (COIs) and cost-effectiveness analyses (CEAs) of eating disorders (EDs) and to describe their methodological quality. Method: A systematic literature search was done. Search results passed through a selection process, included studies were classified as COIs, CEAs, or other cost studies (OCS). Costs were inflated and converted to 2008 US$ purchasing power parities (PPP). Quality criteria were developed and applied to each study. Results: Five COI, two CEA, and eleven OCS were reviewed. Most studies focused on anorexia nervosa and bulimia nervosa. Annual costs per patient ranged from 1,288 to 8,042 US$-PPP. All interventions, investigated in CEA, were more effective and less costly than the alternative treatments. Discussion: The number of publications investigating costs in EDs has increased recently. However, no COI provided a comprehensive estimate of costs, and the comparability of CEA was limited. Nonetheless, the results indicate that the costs arising from EDs are substantial. (C) 2012 by Wiley Periodicals, Inc.