Journal
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
Volume 55, Issue 4-5, Pages 377-382Publisher
UNIV BASQUE COUNTRY UPV-EHU PRESS
DOI: 10.1387/ijdb.103215ac
Keywords
angiogenesis assay; endothelial cell; in vtro model; in vivo model
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Funding
- Romanian Ministry of Research and Education [PN II 41-054/2007]
- MIUR, Rome
- Fondazione Cassa di Risparmio di Puglia, Bari, Italy
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The major problem with angiogenesis research is the choice of an appropriate assay. Currently, many in vitro and in vivo techniques are available for research into the functions of endothelial cells during angiogenesis. In this historical review article, we describe and evaluate the methodology and specific features of some of the most frequently used of these assays.
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