Journal
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
Volume 68, Issue -, Pages 48-49Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijbiomac.2014.04.004
Keywords
Porphyra yezoensis; Hypolipidemic activity; Polysaccharides
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This study was performed to investigate the hypolipidemic effect of the polysaccharides extracted from Porphyra yezoensis. Male Sprague-Dawley rats were divided into three groups and orally treated with diets containing either high fat, P. yezoensis polysaccharides (PPs), or normal fat. Treatment of male Sprague-Dawley rats with PPs led not only to significant decreases in plasma triacylglycerol, total cholesterol, and plasma low-density lipoprotein cholesterol and an increase in plasma high-density lipoprotein cholesterol, but also to significant decreases in liver weight, triacylglycerol and cholesterol. Therefore, the results suggest that PPs had a high hypolipidemic activity and could be used as a potential therapeutic agent for hyperlipidemia. (C) 2014 Elsevier B.V. All rights reserved.
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