Journal
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
Volume 69, Issue -, Pages 442-446Publisher
ELSEVIER
DOI: 10.1016/j.ijbiomac.2014.05.062
Keywords
Modified starch; Polybutadiene; Transdermal; Drug delivery
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Transdermal drug delivery systems are topically administered medicaments in the form of patches that deliver drugs for systemic effects at a predetermined and controlled rate. It works very simply in which drug is applied inside the patch and it is worn on skin for long period of time. Polymer matrix, drug, permeation enhancers are the main components of transdermal drug delivery systems. The objective of the present study was to develop the modified starch and 1,4-cis polybutadiene nanoparticles as novel polymer matrix system. We have been studied the properties of a novel transdermal drug delivery system with clonidine as drug model. (C) 2014 Elsevier B.V. All rights reserved.
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