Journal
INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
Volume 32, Issue 9, Pages 537-544Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/039139880903200902
Keywords
Enterococcus faecalis; Staphylococcus aureus; Fratricide; Altruistic suicide; Autolysis
Categories
Funding
- American Heart Association [0660072Z, 0860084Z]
- Terry C. Johnson Cancer Center at Kansas State University
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Bacterial autolysis has recently been identified as a key mechanism that regulates different phases of biofilm development including microcolony formation and dispersal. However such autolytic measures are limited to a subfraction of cells within the entire biofilm population. Here we speculate on the role biofilm heterogeneity plays in limiting autolysis within biofilms and further describe the molecular regulation of suicidal and fratricidal mechanisms in biofilm development of Staphylococcus aureus and Enterococcus faecalis. (Int J Artif Organs 2009; 32: 537-44)
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