Journal
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Volume 33, Issue 2, Pages 125-129Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijantimicag.2008.07.029
Keywords
Escherichia coli; Antibiotic resistance; Commensal bacteria; Remote community; Peruvian Amazonas
Funding
- European Commission [ICA4-CT-2001-10014]
- European Society of Clinical Microbiology and Infectious Diseases (ESCMID)
Ask authors/readers for more resources
In a very remote human community of the Peruvian Amazonas with minimal antibiotic exposure, high levels of acquired resistance to the oldest antibiotics ( ampicillin, tetracycline, trimethoprim/sulfamethoxazole, streptomycin and chloramphenicol) were detected in commensal Escherichia coli, with remarkable diversity of resistant clones and of resistance genes and plasmids. This pattern was similar overall to that previously observed in a very remote community of Bolivia. It was also similar to that observed in the nearest urban area, except for a lower dominance of resistant isolates and the absolute lack of quinolone resistance in the remote community. Present findings suggest that antibiotic resistance observed in remote communities with minimal antibiotic exposure is a general phenomenon contributed by complex mechanisms and provide new insights into the mechanisms involved in this phenomenon. (C) 2008 Elsevier B. V. and the International Society of Chemotherapy. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available