Journal
INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH
Volume 83, Issue 3, Pages 176-187Publisher
HOGREFE AG-HOGREFE AG SUISSE
DOI: 10.1024/0300-9831/a000158
Keywords
Malawi; women; diet composites; plasma Zn; Se status; body iron; anemia
Categories
Funding
- UK National Environment Research Council (NERC) [NE/1003347/1]
- UK Department for International Development (DFID)
- Economic and Social Research Council (ESRC) under the Ecosystems Services for Poverty Alleviation (ESPA) scheme
- Universities of Otago, East Anglia
- Universities of Otago, Nottingham
- British Geological Survey
- Biotechnology and Biological Sciences Research Council [BB/G005656/1] Funding Source: researchfish
- Natural Environment Research Council [bgs04003, NE/I003347/1] Funding Source: researchfish
- BBSRC [BB/G005656/1] Funding Source: UKRI
- NERC [bgs04003, NE/I003347/1] Funding Source: UKRI
Ask authors/readers for more resources
Background: Zinc deficiency is often associated with nutritional iron deficiency (ID), and may be exacerbated by low selenium status. Aim: To investigate risk of iron and zinc deficiency in women with contrasting selenium status. Methods: In a cross-sectional study, 1-day diet composites and blood samples were collected from self-selected Malawian women aged 18-50 years from low- (Zombwe) (n=60) and high-plant-available soil selenium (Mikalango) (n=60) districts. Diets were analyzed for trace elements and blood for biomarkers. Results: Zinc deficiency (>90 %) was greater than ID anemia (6 %), or ID (5 %), attributed to diets low in zinc (median 5.7 mg/day) with high phytate:zinc molar ratios (20.0), but high in iron (21.0 mg/day) from soil contaminant iron. Zombwe compared to Mikalango women had lower (p<0.05) intakes of selenium (6.5 vs. 55.3 mu g/day), zinc (4.8 vs. 6.4 mg/day), iron (16.6 vs. 29.6 mg/day), lower plasma selenium (0.72 vs. 1.60 mu mol/L), and higher body iron (5.3 vs. 3.8 mg/kg), although plasma zinc was similar (8.60 vs. 8.87 mu mol/L). Body iron and plasma zinc were positive determinants of hemoglobin. Conclusion: Risk of zinc deficiency was higher than ID and was shown not to be associated with selenium status. Plasma zinc was almost as important as body iron as a hemoglobin determinant.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available