Journal
INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH
Volume 80, Issue 1, Pages 32-44Publisher
HOGREFE PUBLISHING CORP
DOI: 10.1024/0300-9831/a000004
Keywords
Vitamin A; age; socio-demographic characteristics; diet; alcohol
Categories
Funding
- French National Agency for Research
- Association Internationale pour la Recherche sur la Maladie d'Alzheimer (AIRMA)
- Regional Council of Aquitaine
- Caisse Nationale Maladie des Travailleurs Salaries
- Direction Generale de la Sante
- Mutuelle Generale de l'Education Nationale
- Institut de la Longevite
- Regional Councils of Aquitaine and Bourgogne
- Fondation de France
- Ministry of Research - INSERM
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The objective was to describe retinol plasma concentration and its association with socio-demographic characteristics and dietary habits in French older persons. The study population consisted of 1.664 subjects aged 65 + from Bordeaux (France), included in the Three-City cohort. Retinol plasma concentration was determined in fasting blood samples. Dietary assessment was performed by a food frequency questionnaire allowing estimation of weekly intake of dietary sources of vitamin A or provitamin A. The weekly number of glasses of alcohol was also recorded. Age, sex, marital status, educational and income levels, body-mass index (BMI), and smoking were registered. Cross-sectional analysis of the association between plasma retinol and socio-demographic characteristics and dietary habits was performed by multilinear regression. Mean plasma retinol was close to the homeostatically regulated concentration of 2.0 mu mol/L but ranged from 0.35 to 6.77 mu mol/L. It was higher in women and divorced or separated individuals, and increased with income but not with age or educational level. Plasma retinol was positively and independently associated with the frequency of offal consumption and to the number of glasses of alcohol consumed per week. These results allow targeting older individuals who are at risk of either excessive or deficient vitamin A status and who should benefit from dietary counseling.
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