Journal
INTERNATIONAL JOURNAL FOR PARASITOLOGY
Volume 43, Issue 2, Pages 125-132Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.ijpara.2012.09.008
Keywords
Babesia; Babesiosis; Tick-fever; Drugs; Vaccines; Genomics
Categories
Funding
- Australian Research Council
- Australian Postgraduate Award
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Bovine babesiosis caused by the protozoan parasite, Babesia bovis, remains a significant cause of avoidable economic losses to the livestock industry in many countries throughout the world. The molecular mechanisms underlying the pathophysiology of severe disease in susceptible cattle are not well understood and the tools available to study the biology of the parasite, including technologies for genetic manipulation, have only recently been developed. Recent availability of multiple parasite genomes and bioinformatic tools, in combination with the development of new biological reagents, will facilitate our better understanding of the parasite. This will ultimately assist in the identification of novel targets for the development of new therapeutics and vaccines. Here we describe some recent advances in Babesia research and highlight some important challenges for the future. (C) 2012 Australian Society for Parasitology Inc. Published by Elsevier Ltd. All rights reserved.
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