Journal
INTERNATIONAL IMMUNOPHARMACOLOGY
Volume 11, Issue 3, Pages 331-341Publisher
ELSEVIER
DOI: 10.1016/j.intimp.2010.08.014
Keywords
Curcumin; Anti-inflammatory; Anti-cancerous; Immune and metabolic diseases
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Inflammation is a disease of vigorous uncontrolled activated immune responses. Overwhelming reports have suggested that the modulation of immune responses by curcumin plays a dominant role in the treatment of inflammation and metabolic diseases. Observations from both in-vitro and in-vivo studies have provided strong evidence towards the therapeutic potential of curcumin. These studies have also identified a plethora of biological targets and intricate mechanisms of action that characterize curcumin as a potent 'drug' for numerous ailments. During inflammation the functional influence of lymphocytes and the related cross-talk can be modulated by curcumin to achieve the desired immune status against diseases. This review describes the regulation of immune responses by curcumin and effectiveness of curcumin in treatment of diseases of diverse nature. (c) 2010 Elsevier B.V. All rights reserved.
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