Journal
INTERNAL MEDICINE JOURNAL
Volume 39, Issue 3, Pages 179-190Publisher
WILEY
DOI: 10.1111/j.1445-5994.2008.01822.x
Keywords
polymyositis; dermatomyositis; inclusion body myositis; autoantibody
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Funding
- Royal Adelaide Hospital/Institute of Medical and Veterinary Science Research Committee
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The idiopathic inflammatory myopathies are a group of systemic autoimmune syndromes characterized by striated muscle inflammation. Here, we discuss the clinical features of this group of cond2itions and review the recent developments in the understanding of the pathogenesis and immunogenetics of the idiopathic inflammatory myopathies. The role of myositis-specific autoantibodies and their clinical significance and an overview of management are also provided.
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