Journal
INTERNAL MEDICINE
Volume 52, Issue 5, Pages 629-632Publisher
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.52.7544
Keywords
hemophagocytic syndrome; human immunodeficiency virus; acute HIV infection; antiretroviral therapy
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Funding
- Ministry of Education, Culture, Sports, Science and Technology (MEXT)
- Global COE Program (Center of Education and Research for Advanced Genome-Based Medicine - For personalized medicine and the control of worldwide infectious diseases) of MEXT
- Ministry of Health, Labor and Welfare of Japan [H24-AIDS-002]
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Hemophagocytic syndrome (HPS) is an unrecognized complication occurring in the acute stage of human immunodeficiency virus (HIV) infection that is seldom reported in the literature. We herein present a case of HPS that occurred during the seroconversion stage of HIV infection. In this case, pancytopenia and liver dysfunction related to HPS recovered after the initiation of antiretroviral therapy (ART). This report indicates the importance of early recognition of HPS and suggests that prompt initiation of ART has the potential to control HPS in the acute stage of HIV infection.
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