Journal
INTERNAL MEDICINE
Volume 52, Issue 10, Pages 1095-1099Publisher
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.52.9477
Keywords
systemic vasculitis; interstitial pneumonia; rapidly progressive glomerulonephritis; BPI-ANCA; x-ANCA
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Myeloperoxidase-and proteinase 3-anti-neutrophil cytoplasmic antibodies (ANCAs) are often negative in cases in which systemic vasculitis is highly suspected. We herein present a case of bactericidal/permeability increasing protein (BPI)-ANCA-positive systemic vasculitis. This case highlights the possible role of BPI-ANCA in the pathogenesis of systemic vasculitis as well as the possible use of BPI as a diagnostic tool. The accumulation of further case-based reports is expected to shed some light on the pathogesis of systemic vasculitis.
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