Journal
INTERNAL MEDICINE
Volume 51, Issue 18, Pages 2587-2590Publisher
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.51.8081
Keywords
antineutrophil cytoplasmic antibody (ANCA); rapidly progressive glomerulonephritis (RPGN); subacute bacterial endocarditis (SBE)
Categories
Ask authors/readers for more resources
Patients with bacterial endocarditis often have renal complications. This report presents the case of an elderly man with rapidly progressive glomerulonephritis (RPGN) associated with subacute bacterial endocarditis (SBE) due to Enterococcus faecalis infection. The patient was positive for anti-proteinase 3-antineutrophil cytoplasmic antibody (PR3-ANCA) and rheumatoid factor (RF) with hypocomplementemia. Treatment for SBE with antibiotics and the surgical replacement of the affected valves resulted in an improvement of RPGN, the disappearance of PR3-ANCA and RF, and the normalization of hypocomplementemia. This rare case suggests the importance of recognizing the cause of positive PR3-ANCA, because SBE could be an occult cause of RPGN mimicking ANCA-associated vasculitis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available