Journal
INSECT MOLECULAR BIOLOGY
Volume 20, Issue 2, Pages 189-199Publisher
WILEY
DOI: 10.1111/j.1365-2583.2010.01057.x
Keywords
chemosensory receptor; ionotropic receptor; glutamate receptor; olfaction; Spodoptera littoralis
Categories
Funding
- Institut National de la Recherche Agronomique (INRA) AIP
- Universite Pierre et Marie Curie
- INRA
- [ANR-07-NEURO-037-01]
- [ANR-09-BLAN-0239-01]
Ask authors/readers for more resources
A new family of candidate chemosensory ionotropic receptors (IRs) related to ionotropic glutamate receptors (iGluRs) was recently discovered in Drosophila melanogaster. Through Blast analyses of an expressed sequenced tag library prepared from male antennae of the noctuid moth Spodoptera littoralis, we identified 12 unigenes encoding proteins related to D. melanogaster and Bombyx mori IRs. Their full length sequences were obtained and the analyses of their expression patterns suggest that they were exclusively expressed or clearly enriched in chemosensory organs. The deduced protein sequences were more similar to B. mori and D. melanogaster IRs than to iGluRs and showed considerable variations in the predicted ligand-binding domains; none have the three glutamate-interacting residues found in iGluRs, suggesting different binding specificities. Our data suggest that we identified members of the insect IR chemosensory receptor family in S. littoralis and we report here the first demonstration of IR expression in Lepidoptera.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available