Journal
INORGANIC CHEMISTRY
Volume 51, Issue 24, Pages 13075-13077Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ic301822r
Keywords
-
Categories
Funding
- JSPS [23685039]
- Naito Foundation
- Grants-in-Aid for Scientific Research [23685039] Funding Source: KAKEN
Ask authors/readers for more resources
A Hg2+-selective fluorescent sensor, RosHg, has been developed based on a rosamine platform. RosHg exhibited a similar to 20-fold increase in fluorescence emission upon binding with Hg2+, and the enhanced fluorescence was immediately decreased when glutathione was added to a solution of the Hg-RosHg complex. The dissociation constant for the Hg2+ complex was determined to be 0.10 fM by using a set of Hg2+/Mg2+/ethylenediaminetetra-acetic acid buffer solutions. Confocal microscopy experiments demonstrated that this sensor can monitor changes of the Hg2+ level in the mitochondria of living cells.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available