4.5 Review

Inflammatory Bowel Disease: An Overview of Immune Mechanisms and Biological Treatments

Related references

Note: Only part of the references are listed.
Review Health Care Sciences & Services

Biologics in the management of ulcerative colitis - comparative safety and efficacy of TNF-α antagonists

Rebecca Fausel et al.

THERAPEUTICS AND CLINICAL RISK MANAGEMENT (2015)

Review Immunology

Targets for new immunomodulation strategies in inflammatory bowel disease

Giovanni Monteleone et al.

AUTOIMMUNITY REVIEWS (2014)

Review Immunology

Innate and adaptive immunity in inflammatory bowel disease

Alessandra Geremia et al.

AUTOIMMUNITY REVIEWS (2014)

Review Immunology

Diagnosis and classification of Crohn's disease

Martin W. Laass et al.

AUTOIMMUNITY REVIEWS (2014)

Article Gastroenterology & Hepatology

Association Between Pharmacokinetics of Adalimumab and Mucosal Healing in Patients With Inflammatory Bowel Diseases

Xavier Roblin et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2014)

Article Gastroenterology & Hepatology

Biosimilars in the therapy of inflammatory bowel diseases

Tibor Hlavaty et al.

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2014)

Review Biotechnology & Applied Microbiology

New biologic therapeutics for ulcerative colitis and Crohn's disease

Shilan Mozaffari et al.

EXPERT OPINION ON BIOLOGICAL THERAPY (2014)

Article Gastroenterology & Hepatology

Subcutaneous Golimumab Maintains Clinical Response in Patients With Moderate-to-Severe Ulcerative Colitis

William J. Sandborn et al.

GASTROENTEROLOGY (2014)

Review Gastroenterology & Hepatology

Future directions in inflammatory bowel disease management

Geert R. D'Haens et al.

JOURNAL OF CROHNS & COLITIS (2014)

Article Medicine, General & Internal

Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial

Severine Vermeire et al.

LANCET (2014)

Article Gastroenterology & Hepatology

Natural history and long-term clinical course of Crohn's disease

Hugh James Freeman

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

Article Gastroenterology & Hepatology

Performance of the Montreal classification for inflammatory bowel diseases

Lieke M. Spekhorst et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

Article Medicine, General & Internal

Incidences of Serious Infections and Tuberculosis among Patients Receiving Anti-Tumor Necrosis Factor-α Therapy

In Kyung Yoo et al.

YONSEI MEDICAL JOURNAL (2014)

Review Gastroenterology & Hepatology

Current and emerging maintenance therapies for ulcerative colitis

Anthony O'Connor et al.

EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY (2014)

Article Medicine, Research & Experimental

A guide to prepare patients with inflammatory bowel diseases for anti-TNF-α therapy

Adérson Omar Mourão Cintra Damião

MEDICAL SCIENCE MONITOR (2014)

Review Medicine, General & Internal

Methotrexate for induction of remission in refractory Crohn's disease

John W. D. McDonald et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2014)

Review Immunology

Cytokines in inflammatory bowel disease

Markus F. Neurath

NATURE REVIEWS IMMUNOLOGY (2014)

Review Gastroenterology & Hepatology

Review article: immunogenicity of anti-TNF biologics in IBD - the role of patient, product and prescriber factors

A. C. Moss et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2013)

Review Cell Biology

Crohn's disease: A review of treatment options and current research

Sean Bandzar et al.

CELLULAR IMMUNOLOGY (2013)

Article Pharmacology & Pharmacy

Janus Kinase Inhibition with Tofacitinib: Changing the Face of Inflammatory Bowel Disease Treatment

Lucine Vuitton et al.

CURRENT DRUG TARGETS (2013)

Review Gastroenterology & Hepatology

Regulatory cell populations in the intestinal mucosa

Wendy A. Goodman et al.

CURRENT OPINION IN GASTROENTEROLOGY (2013)

Review Gastroenterology & Hepatology

Adherence to Anti-TNF Therapy in Inflammatory Bowel Diseases: A Systematic Review

Anthony Lopez et al.

INFLAMMATORY BOWEL DISEASES (2013)

Article Gastroenterology & Hepatology

ECCO position statement: The use of biosimilar medicines in the treatment of inflammatory bowel disease (IBD)

Silvio Danese et al.

JOURNAL OF CROHNS & COLITIS (2013)

Editorial Material Gastroenterology & Hepatology

IBD Golimumab in ulcerative colitis: a 'menage a trois' of drugs

Silvio Danese

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2013)

Review Rheumatology

Immunogenicity of anti-TNF biologic therapies for rheumatoid arthritis

Pauline A. van Schouwenburg et al.

NATURE REVIEWS RHEUMATOLOGY (2013)

Article Medicine, General & Internal

Vedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis

Brian G. Feagan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Medicine, General & Internal

Vedolizumab as Induction and Maintenance Therapy for Crohn's Disease

William J. Sandborn et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Review Gastroenterology & Hepatology

Comprehensive review: antitumor necrosis factor agents in inflammatory bowel disease and factors implicated in treatment response

Gary R. Lichtenstein

THERAPEUTIC ADVANCES IN GASTROENTEROLOGY (2013)

Review Immunology

Autophagy in infection, inflammation and immunity

Vojo Deretic et al.

NATURE REVIEWS IMMUNOLOGY (2013)

Article Dermatology

Immunogenicity in Biologic Therapy: Implications for Dermatology

J. M. Carrascosa

ACTAS DERMO-SIFILIOGRAFICAS (2013)

Review Immunology

Immunogenicity to Biologics: Mechanisms, Prediction and Reduction

Swaminathan Sethu et al.

ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS (2012)

Editorial Material Immunology

Tolerance and Inflammation at the Gut Mucosa

Ana Maria C. Faria et al.

CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2012)

Review Medicine, Research & Experimental

Th17-Related Cytokines in Inflammatory Bowel Diseases: Friends or Foes?

I. Monteleone et al.

CURRENT MOLECULAR MEDICINE (2012)

Review Pediatrics

The use of biologic agents in pediatric inflammatory bowel disease

Linda S. Yang et al.

CURRENT OPINION IN PEDIATRICS (2012)

Article Biotechnology & Applied Microbiology

A review and expert opinion of the use of certolizumab for Crohn's disease

Ashley T. Evans et al.

EXPERT OPINION ON BIOLOGICAL THERAPY (2012)

Editorial Material Gastroenterology & Hepatology

Dead on Arrival: Understanding the Failure of CTLA4-Immunoglobulin Therapy in Inflammatory Bowel Disease

Lloyd Mayer et al.

GASTROENTEROLOGY (2012)

Article Gastroenterology & Hepatology

Adalimumab Induces and Maintains Clinical Remission in Patients With Moderate-to-Severe Ulcerative Colitis

William J. Sandborn et al.

GASTROENTEROLOGY (2012)

Review Gastroenterology & Hepatology

Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review

Natalie A. Molodecky et al.

GASTROENTEROLOGY (2012)

Article Gastroenterology & Hepatology

Vedolizumab for the treatment of active ulcerative colitis: A randomized controlled phase 2 dose-ranging study

Asit Parikh et al.

INFLAMMATORY BOWEL DISEASES (2012)

Review Immunology

Oral tolerance to food protein

O. Pabst et al.

MUCOSAL IMMUNOLOGY (2012)

Article Medicine, General & Internal

Ustekinumab Induction and Maintenance Therapy in Refractory Crohn's Disease

William J. Sandborn et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Article Multidisciplinary Sciences

Intestinal CX3C chemokine receptor 1high (CX3CR1high) myeloid cells prevent T-cell-dependent colitis

Hisako Kayama et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Gastroenterology & Hepatology

Changes of the cytokine profile in inflammatory bowel diseases

Gyoergyi Muzes et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2012)

Article Medicine, Research & Experimental

Screening of Budesonide Nanoformulations for Treatment of Inflammatory Bowel Disease in an Inflamed 3D Cell-Culture Model

Fransisca Leonard et al.

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION (2012)

Review Gastroenterology & Hepatology

The IL-23/IL-17 pathway in inflammatory bowel disease

Alessandra Geremia et al.

EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY (2012)

Review Medicine, General & Internal

Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis

Brian G. Feagan et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2012)

Article Medical Laboratory Technology

Autoantibodies to GP2, the major zymogen granule membrane glycoprotein, are new markers in Crohn's disease

Dirk Roggenbuck et al.

CLINICA CHIMICA ACTA (2011)

Article Gastroenterology & Hepatology

Epidemiology and Natural History of Inflammatory Bowel Diseases

Jacques Cosnes et al.

GASTROENTEROLOGY (2011)

Review Immunology

Oral tolerance

Howard L. Weiner et al.

IMMUNOLOGICAL REVIEWS (2011)

Article Gastroenterology & Hepatology

Certolizumab Pegol in Patients With Moderate to Severe Crohn's Disease and Secondary Failure to Infliximab

William J. Sandborn et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2010)

Review Immunology

NOD2-associated diseases: Bridging innate immunity and autoinflammation

Arturo Borzutzky et al.

CLINICAL IMMUNOLOGY (2010)

Article Gastroenterology & Hepatology

Appropriateness of Crohn's Disease Therapy in Gastroenterological Rehabilitation

Christoph Reichel et al.

DIGESTION (2010)

Article Gastroenterology & Hepatology

Identification of complement C3 as an autoantigen in inflammatory bowel disease

Brita Ardesjo Lundgren et al.

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2010)

Review Immunology

Use of immunomodulators and biologic therapies in children with inflammatory bowel disease

Athos Bousvaros

EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2010)

Review Gastroenterology & Hepatology

Role of Transforming Growth Factor-β in Inflammatory Bowel Disease and Colitis-associated Colon Cancer

Linda A. Feagins

INFLAMMATORY BOWEL DISEASES (2010)

Article Gastroenterology & Hepatology

Inflammatory Bowel Disease Developing in Paediatric and Adult Age

Graziella Guariso et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2010)

Review Gastroenterology & Hepatology

Biological Therapies for Inflammatory Bowel Diseases

Paul Rutgeerts et al.

GASTROENTEROLOGY (2009)

Review Dentistry, Oral Surgery & Medicine

Inflammatory bowel disease

Mahnaz Fatahzadeh

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY (2009)

Article Gastroenterology & Hepatology

Adalimumab in ulcerative colitis: Two cases of mucosal healing and clinical response at two years

Manuel Barreiro-de Acosta et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2009)

Review Gastroenterology & Hepatology

Potential role of Th17 cells in the pathogenesis of inflammatory bowel disease

Zhan-Ju Liu et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2009)

Article Gastroenterology & Hepatology

Successful use of adalimumab for treating fistulizing Crohn's disease with pyoderma gangrenosum: Two birds with one stone

Eva Zold et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2009)

Article Gastroenterology & Hepatology

Selecting appropriate anti-TNF agents in inflammatory bowel disease

Laura Yun et al.

Expert Review of Gastroenterology & Hepatology (2009)

Article Gastroenterology & Hepatology

Efficacy and safety of tumor necrosis factor antagonists in Crohn's disease: Meta-analysis of placebo-controlled trials

Laurent Peyrin-Biroulet et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2008)

Article Immunology

TGF-β1 and Smad7 in the regulation of IBD

G. Monteleone et al.

MUCOSAL IMMUNOLOGY (2008)

Editorial Material Gastroenterology & Hepatology

Current view of the immunopathagenesis in inflammatory bowel disease and its implications fair therapy

M. I. Torres et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2008)

Review Immunology

The genetics and immunopathogenesis of inflammatory bowel disease

Judy H. Cho

NATURE REVIEWS IMMUNOLOGY (2008)

Review Gastroenterology & Hepatology

The management of steroid dependency in ulcerative colitis

G. Bianchi Porro et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2007)

Article Pharmacology & Pharmacy

New onset of atrial fibrillation after introduction of azathioprine in ulcerative colitis: case report and review of the literature

Andrea Cassinotti et al.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY (2007)

Article Oncology

Certolizumab pegol in Crohn's disease

Stephanie K. A. Blick et al.

BIODRUGS (2007)

Article Immunology

Interferon-gamma is causatively involved in experimental inflammatory bowel disease in mice

R. Ito et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2006)

Article Gastroenterology & Hepatology

Onercept for moderate-to-severe Crohn's disease: A randomized, double-blind, placebo-controlled trial

Paul Rutgeerts et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2006)

Review Gastroenterology & Hepatology

Review article: infliximab therapy for inflammatory bowel disease - seven years on

P Rutgeerts et al.

ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2006)

Article Gastroenterology & Hepatology

Small intestinal bacterial overgrowth: Roles of antibiotics, prebiotics, and Probiotics

EMM Quigley et al.

GASTROENTEROLOGY (2006)

Review Immunology

Oral tolerance: Therapeutic implications for autoimmune diseases

Ana M. C. Faria et al.

CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2006)

Review Immunology

Oral tolerance

AMC Faria et al.

IMMUNOLOGICAL REVIEWS (2005)

Article Medicine, General & Internal

Treatment of ulcerative colitis with a humanized antibody to the α4β7 integrin

BG Feagan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Review Immunology

NOD2 and Crohn's disease: Loss or gain of function?

L Eckmann et al.

IMMUNITY (2005)

Review Pharmacology & Pharmacy

Biologic therapy for inflammatory bowel disease

S Ardizzone et al.

DRUGS (2005)

Article Gastroenterology & Hepatology

Azathioprine and mesalamine for prevention of relapse after conservative surgery for Crohn's disease

S Ardizzone et al.

GASTROENTEROLOGY (2004)

Review Gastroenterology & Hepatology

Guidelines for the management of inflammatory bowel disease in adults

MJ Carter et al.

Article Gastroenterology & Hepatology

Severe villus atrophy and chronic malabsorption induced by azathioprine

TR Ziegler et al.

GASTROENTEROLOGY (2003)

Article Medicine, Research & Experimental

Azathioprine: old drug, new actions

JS Maltzman et al.

JOURNAL OF CLINICAL INVESTIGATION (2003)

Article Nutrition & Dietetics

The immune system: a target for functional foods?

PC Calder et al.

BRITISH JOURNAL OF NUTRITION (2002)

Review Biochemistry & Molecular Biology

The role of Th1/Th2 polarization in mucosal immunity

MF Neurath et al.

NATURE MEDICINE (2002)

Article Gastroenterology & Hepatology

The immunology of inflammatory bowel disease

S Plevy

GASTROENTEROLOGY CLINICS OF NORTH AMERICA (2002)

Article Gastroenterology & Hepatology

Etanercept for active Crohn's disease: A randomized, double-blind, placebo-controlled trial

WJ Sandborn et al.

GASTROENTEROLOGY (2001)

Article Gastroenterology & Hepatology

Infliximab in the treatment of severe, steroid-refractory ulcerative colitis: A pilot study

BE Sands et al.

INFLAMMATORY BOWEL DISEASES (2001)