Journal
INHALATION TOXICOLOGY
Volume 23, Issue 2, Pages 112-120Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/08958378.2010.548838
Keywords
welding; chromium; lung cancer; strain A mice; bronchoalveolar lavage
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Debate exists as to whether welding fume is carcinogenic, but epidemiological evidence suggests that welders are an at-risk population for development of lung cancer. Our objective was to expose, by inhalation, lung tumor susceptible (A/J) and resistant C57BL/6J (B6) mice to stainless steel (SS) welding fume containing carcinogenic metals and characterize the lung-inflammatory and tumorigenic response. Male mice were exposed to air or gas metal arc (GMA)-SS welding fume at 40 mg/m
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