Journal
INHALATION TOXICOLOGY
Volume 22, Issue 3, Pages 245-252Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/08958370903207274
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Funding
- US Environmental Protection Agency [R-827354]
- NIEHS Center [P30ESO1247]
- Focus-Network of Aerosols and Health, Helmholtz Zentrum (HMGU), Germany
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In this explorative analysis, we found an immediate decrease of polymorphonuclear leukocytes in response to an increase of most gaseous and particulate pollutants. Lymphocytes increased within 24 h in association with all gaseous pollutants but showed only minor effects in regard to particulate air pollution. Monocytes showed an increase associated with ultrafine particles, and nitrogen monoxide. The effect had two peaks in time, one 0-23 h before blood withdrawal and a second one with a time lag of 48-71 h. The increase of particulate and gaseous air pollution was associated with multiple changes in the differential white blood cell count in patients with chronic pulmonary diseases.
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