Journal
INFECTION GENETICS AND EVOLUTION
Volume 20, Issue -, Pages 298-303Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.meegid.2013.09.004
Keywords
Influenza A virus; Animal origin influenza A virus; Amantadine resistance; Drug resistance; Phylogenetic analysis; Geospatial analysis
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Funding
- National Science Foundation (NSF) [BCS-0717688]
- UNC Infectious Diseases Pathogenesis Training Fellowship
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In China, approximately 20% of the animal original influenza A viruses have molecular markers of amantadine resistance. Through phylogenetic data analyses and geospatial statistical analyses, this study suggests emergence of amantadine resistance in animal influenza could be due to selection pressures in China, for example, amantadine usage in some areas. (C) 2013 Elsevier B. V. All rights reserved.
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