Journal
INFECTION GENETICS AND EVOLUTION
Volume 11, Issue 8, Pages 1862-1867Publisher
ELSEVIER
DOI: 10.1016/j.meegid.2011.07.013
Keywords
Hantavirus; Thottapalayam virus; Phylogeny; Suncus murinus
Categories
Funding
- Chinese Ministry of Science and Technology [2002DIB40095, 2003BA712A08-02, 2008ZX10004-008]
- State Key Laboratory for Infection Disease Prevention and Control [2011SKLID101]
Ask authors/readers for more resources
Recently, many novel hantavirus species carried by insectivore had been found. In order to know whether the insectivore-associated hantaviruses exist in China, Asian house shrew (Suncus murinus) were analyzed for the presence of hantaviruses. 362 Asian house shrews were captured in Wenzhou of Zhejiang province. Hantavirus-specific RNA was detected by RT-PCR in lung tissue samples of six shrews. The complete hantavirus S and M segment sequences and also partial L segment sequences were successfully recovered. Pairwise comparison of the nucleotide and deduced amino acid sequences showed that the newly discovered virus strains are most closely related to Thottapalayam virus (TPMV) isolated from S. murinus in India, with 82.5-84.7% sequence identity at the nucleotide level and 95.0-98.2% at the amino acid level. Corresponding sequences of Imjin virus (MJNV) were more distant and other rodent- and insectivore-associated hantaviruses appeared even less related. Phylogenetic analysis revealed that the new variants formed a distinct lineage within TPMV. (C) 2011 Published by Elsevier B.V.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available